Background
Short-term mechanical circulatory support may be lifesaving in patients with right
ventricular (RV) failure related to post-cardiotomy cardiogenic shock (PCCS), cardiac
transplantation (CTx), and long-term therapy with a left ventricular assist device
(LVAD). This study evaluates our clinical experience using the CentriMag (Levitronix
LLC, Waltham, Mass) system for temporary mechanical RV support.
Methods
A retrospective review was performed of 29 patients (mean age, 57 ± 14 years) in whom
the CentriMag system was used for RV support from September 2005 to March 2008.
Results
The indication for RV support was PCCS in 7 (24%), CTx in 10 (35%), and LVAD placement
in 12 (41%). The mean support time was 8 ± 8 days. The device was successfully weaned
in 3 PCCS patients (43%), 7 CTx patients (70%), and 7 LVAD patients (58%). Complications
included major infection (pneumonia, sepsis, or LVAD pocket infection) in 13 (45%),
arrhythmia in 13 (45%), reoperation for bleeding in 10 (35%), stroke/encephalopathy
in 3 (10%), and air embolism in 1 (3%). Early mortality (< 30 days or before discharge)
occurred in 14 patients (48%) of which 9 (31%) died with the device in place. Late
death occurred in 2 of 15 patients (13%) who survived to discharge. There were no
device failures.
Conclusions
The CentriMag system provides effective temporary mechanical circulatory support for
RV failure. Ease of implantation and a high rate of successful device weaning justify
the use of the CentriMag system for temporary RV support.
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References
- Mechanical support for isolated right ventricular failure in patients after cardiotomy.J Heart Lung Transplant. 2004; 23: 1371-1375
- Experience with right ventricular assist devices for perioperative right-sided circulatory failure.Ann Thorac Surg. 1996; 61: 305-310
- Right heart failure after left ventricular assist device implantation in patients with chronic congestive heart failure.J Heart Lung Transplant. 2006; 25: 1-6
- INTERMACS database for durable devices for circulatory support: first annual report.J Heart Lung Transplant. 2008; 27: 1065-1072
- Clinical performance with the Levitronix CentriMag short-term ventricular assist device.J Heart Lung Transplant. 2006; 25: 181-186
- Levitronix as a short-term salvage treatment for primary graft failure after heart transplantation.J Heart Lung Transplant. 2006; 25: 495-498
- Levitronix ventricular assist device as a bridge to recovery after profound biventricular heart failure associated with pulmonary aspergillosis.J Heart Lung Transplant. 2007; 26: 345-349
- Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure.J Thorac Cardiovasc Surg. 2007; 134: 351-358
- Connecting the Centrimag Levitronix pump to berlin heart excor cannulae; a new approach to bridge to bridge.J Heart Lung Transplant. 2008; 27: 112-115
- The Papworth experience with the Levitronix CentriMag ventricular assist device.J Heart Lung Transplant. 2008; 27: 158-164
- Bridge to decision using the Levitronix CentriMag short-term ventricular assist device.J Heart Lung Transplant. 2008; 27: 474-478
- Levitronix ventricular assist device as a bridge-to-recovery for post-cardiotomy cardiogenic shock.Int J Cardiol. 2008; (doi:10.1016/j.ijcard.2008.02.002)
- CentriMag left ventricular assist system.Tex Heart Inst J. 2008; 35: 184-185
- Preoperative and postoperative comparison of patients with univentricular and biventricular support with the Thoratec ventricular assist device as a bridge to cardiac transplantation.J Thorac Cardiovasc Surg. 1997; 113: 202-209
- Transplant candidate's clinical status rather than right ventricular function defines need for univentricular versus biventricular support.J Thorac Cardiovasc Surg. 1996; 111: 773-783
- Acute and temporary ventricular support with BioMedicus centrifugal pump.Ann Thorac Surg. 1999; 68: 650-654
- Standard criteria for an acceptable donor heart are restricting heart transplantation.Ann Thorac Surg. 1996; 62: 1268-1275
- Is severe right ventricular failure in left ventricular assist device recipients a risk factor for unsuccessful bridging to transplant and post-transplant mortality.Ann Thorac Surg. 2004; 77: 859-863
Article info
Publication history
Accepted:
April 8,
2009
Received in revised form:
March 13,
2009
Received:
January 13,
2009
Identification
Copyright
© 2009 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.