Abstract
By unloading the failing heart, left ventricular (LV) assist devices (LVADs) provide
a favorable environment for reversing adverse structural and functional cardiac changes.
Prior reports have suggested that an improved native LV function might contribute
to the development of LVAD thrombosis. We used the Interagency Registry for Mechanically
Assisted Circulatory Support and found that LV functional improvement is associated
with a lower risk for device thrombosis. The risk for cerebrovascular accident and
transient ischemic attack was comparable across post-LVAD LV function subgroups, while
the risk of hemolysis was lower in subgroups of patients with better LV function on
LVAD support.
Keywords
Abbreviations:
CVA (Cerebrovascular accident), HF (Heart failure), HR (Hazard ratio), Intermacs (Interagency Registry for Mechanically Assisted Circulatory Support), LV (Left ventricle/left ventricular), LVAD (Left ventricular assist device), LVEF (Left ventricular ejection fraction), TIA (Transient ischemic attack)To read this article in full you will need to make a payment
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References
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Article info
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© Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.
