Intra-Aortic Balloon Pump (IABP) efficacy is critically affected by the inflation/deflation
timing. Balloon deflation may cause a sucking effect, and a steal phenomenon on carotid
flow. Delaying IABP deflation reduces the degree of this flow reversal, but at the
same time exposes patients to the risk of increased proto-systolic afterload with
detrimental effects on the LV. The purpose of this study was to investigate the effects
of a delayed IABP deflation timing on cerebral blood flow and LV hemodynamics, by
means of simultaneous carotid artery ultrasonography, trans-thoracic echocardiography
and central aortic pressure analysis. Delaying IABP deflation trigger to the beginning
of QRS effectively increased the cerebral blood flow by 20%, mostly by reducing the
reverse component flow caused by the diastolic balloon deflation. Extending the deflation
to the early systole was safe and favourably impacted on cardiac mechanics, increasing
CO by 15% without prolonging LV isovolumetric contraction and ejection phases.
KEYWORDS
Abbreviations:
ADP (augmented diastolic pressure), ASP (assisted systolic pressure), CO (cardiac output), EDP (end-diastolic pressure), IABP (intra-aortic balloon pump), LV (left ventricle), VTI (velocity-time integral)To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: December 11, 2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 International Society for Heart and Lung Transplantation. All rights reserved.
