Advertisement
The Journal of Heart and Lung Transplantation
International Society for Heart and Lung Transplantation.

A report of the first pediatric heart transplant following donation after circulatory death in the United States using ex-vivo perfusion

Published:September 30, 2022DOI:https://doi.org/10.1016/j.healun.2022.09.016
      Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients.
      • Truby LK
      • Casalinova S
      • Patel CB
      • et al.
      Donation after circulatory death in heart transplantation: history, outcomes, clinical challenges, and opportunities to expand the donor pool.
      We report the first pediatric DCD heart transplantation in the United States (US) using EVP. This report was published with permission from the institutional review board and parental consent and adheres to the ethical statement by the International Society for Heart and Lung Transplantation.

      KEYWORDS

      Abbreviations:

      DCD (donation after circulatory death), EVP (ex-vivo perfusion), LVAD (left ventricular assist device), OCS (organ care system), US (United States)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The Journal of Heart and Lung Transplantation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Truby LK
        • Casalinova S
        • Patel CB
        • et al.
        Donation after circulatory death in heart transplantation: history, outcomes, clinical challenges, and opportunities to expand the donor pool.
        J Card Fail. 2022; 28: 1456-1463
        • Schroder JN
        • Shah A
        • Pretorius V
        • et al.
        Expanding heart transplants from donors after circulatory death (DCD) - results of the first randomized controlled trial using the organ care system (OCS (TM)) heart - (OCS DCD Heart Trial).
        J Heart Lung Transpl. 2022; 41 (S72-S)
        • Rajab TK
        • Singh SK.
        Donation after cardiac death heart transplantation in America is clinically necessary and ethically justified.
        Circ Heart Fail. 2018; 11e004884
        • Chew HC
        • Iyer A
        • Connellan M
        • et al.
        Outcomes of donation after circulatory death heart transplantation in Australia.
        J Am Coll Cardiol. 2019; 73: 1447-1459
        • Messer S
        • Cernic S
        • Page A
        • et al.
        A 5-year single-center early experience of heart transplantation from donation after circulatory-determined death donors.
        J Heart Lung Transplant. 2020; 39: 1463-1475
        • Khushnood A
        • Butt TA
        • Jungschleger J
        • et al.
        Paediatric donation after circulatory determined death heart transplantation using donor normothermic regional perfusion and ex situ heart perfusion: a case report.
        Pediatr Transplant. 2019; 23: e13536
        • Laurence C
        • Nachum E
        • Henwood S
        • et al.
        Pediatric heart transplantation following donation after circulatory death, distant procurement, and ex-situ perfusion.
        J Heart Lung Transplant. 2022; 41: 1104-1113