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The Journal of Heart and Lung Transplantation
International Society for Heart and Lung Transplantation.

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation Report—2019; Focus theme: Donor and recipient size match

      This 36th adult lung and heart-lung transplant report summarizes data from 69,200 adult lung and 4,128 adult heart-lung transplants performed through June 30, 2018 and reported to the International Thoracic Organ Transplant Registry. With each year's report, we now provide more detailed analyses on a particular focus theme important to patient outcomes. Since 2013, these have been donor and recipient age; retransplantation; early graft failure; indication for transplant; allograft ischemic time; and multiorgan transplantation. Although widely accepted as critical to decision making at the time of receipt of an organ donor offer, there is surprisingly little literature outlining current practice and the impact of size (mis-)matching on outcomes. Hence, this year's report focuses on an overall theme of donor and recipient size matching. In addition to reporting donor and recipient height and weight difference for all adult lung and heart-lung transplant recipients stratified by transplant type (bilateral or single) and indication, we report historical trends and associations between size match and survival. The Registry's online slide sets include results from additional analyses and complementary information not included in this publication (see https://ishltregistries.org/registries/slides.asp).
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      References

        • Chambers DC
        • Cherikh WS
        • Goldfarb SB
        • et al.
        The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-fifth adult lung and heart-lung transplant report-2018; Focus theme: multiorgan Transplantation.
        J Heart Lung Transplant. 2018; 37: 1169-1183
        • Goldfarb SB
        • Hayes Jr, D
        • Levvey BJ
        • et al.
        The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation.: twenty-first pediatric lung and heart–lung transplantation report-2018; focus theme: multiorgan transplantation.
        J Heart Lung Transplant. 2018; 37: 1196-1206
        • Rossano JW
        • Cherikh WS
        • Chambers DC
        • et al.
        The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-first pediatric heart transplantation report-2018; Focus theme: multiorgan Transplantation.
        J Heart Lung Transplant. 2018; 37: 1184-1195
        • Khush KK
        • Cherikh WS
        • Chambers DC
        • et al.
        The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-fifth adult heart transplantation Report-2018; focus theme: multiorgan transplantation.
        J Heart Lung Transplant. 2018; 37: 1155-1168
        • Yusen RD
        • Edwards LB
        • Kucheryavaya AY
        • et al.
        The Registry of the International Society for Heart and Lung Transplantation: thirty-first adult lung and heart-lung transplant report—2014; focus theme: retransplantation.
        J Heart Lung Transplant. 2014; 33: 1009-1024
        • Yusen RD
        • Edwards LB
        • Kucheryavaya AY
        • et al.
        The Registry of the International Society for Heart and Lung Transplantation: thirty-second official adult lung and heart-lung transplantation report-2015; focus theme: early graft failure.
        J Heart Lung Transplant. 2015; 34: 1264-1277
        • Yusen RD
        • Edwards LB
        • Dipchand AI
        • et al.
        The Registry of the International Society for Heart and Lung Transplantation: thirty-third adult lung and heart-lung transplant report-2016; focus theme: primary diagnostic indications for transplant.
        J Heart Lung Transplant. 2016; 35: 1170-1184
        • Chambers DC
        • Yusen RD
        • Cherikh WS
        • et al.
        The Registry of the International Society for Heart and Lung Transplantation: thirty-fourth adult lung and heart-lung transplantation report-2017; focus theme: allograft ischemic time.
        J Heart Lung Transplant. 2017; 36: 1047-1059
        • Delom F
        • Danner-Boucher I
        • Dromer C
        • et al.
        Impact of donor-to-recipient weight ratio on survival after bilateral lung transplantation.
        Transplant Proc. 2014; 46: 1517-1522
        • Eberlein M
        • Permutt S
        • Chahla MF
        • et al.
        Lung size mismatch in bilateral lung transplantation is associated with allograft function and bronchiolitis obliterans syndrome.
        Chest. 2012; 141: 451-460
        • Eberlein M
        • Reed RM
        • Bolukbas S
        • et al.
        Lung size mismatch and primary graft dysfunction after bilateral lung transplantation.
        J Heart Lung Transplant. 2015; 34: 233-240
        • Eberlein M
        • Reed RM
        • Maidaa M
        • et al.
        Donor-recipient size matching and survival after lung transplantation. A cohort study.
        Ann Am Thorac Soc. 2013; 10: 418-425
        • Hayden AM
        • Scarlett MV
        • Fox K
        Relationship between donor/recipient lung size mismatch and functional outcome in single lung transplantation for COPD.
        J Transpl Coord. 1996; 6: 155-158
        • Fessart D
        • Dromer C
        • Thumerel M
        • Jougon J
        • Delom F
        Influence of gender donor-recipient combinations on survival after human lung transplantation.
        Transplant Proc. 2011; 43: 3899-3902
        • Iyer A
        • Kumarasinghe G
        • Hicks M
        • et al.
        Primary graft failure after heart transplantation.
        J Transplant. 2011; 2011175768
        • Bergenfeldt H
        • Stehlik J
        • Höglund P
        • Andersson B
        • Nilsson J
        Donor-recipient size matching and mortality in heart transplantation: influence of body mass index and gender.
        J Heart Lung Transplant. 2017; 36: 940-947
        • Khush KK
        • et al.
        The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth Adult Heart Transplantation report - 2019; Focus Theme: Donor and Recipient Size Match.
        J Heart Lung Transplant. 2019; 38: 1056-1066
        • Kilburn KH
        • Warshaw RH
        • Thornton JC
        • Thornton K
        • Miller A
        Predictive equations for total lung capacity and residual volume calculated from radiographs in a random sample of the Michigan population.
        Thorax. 1992; 47: 519-523
        • Paoletti P
        • Viegi G
        • Carrozzi L
        • et al.
        Residual volume in a general population. Effects of body size, age, cigarette smoking, and respiratory symptoms.
        Chest. 1992; 102: 1209-1215
        • Hayes D
        • et al.
        Registry of the International Society for Heart and Lung Transplantation: Twenty-first Pediatric Lung and Heart-Lung Transplantation Report-2019; Focus Theme: Donor and Recipient Size Match.
        J Heart Lung Transplant. 2019; 37: xxxx-xxxx