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The Journal of Heart and Lung Transplantation
International Society for Heart and Lung Transplantation.

Cytokine Expression in the Myocardium Correlates With Cardiac Structural and Functional Improvement Induced By Mechanical Unloading in Chronic Heart Failure

      Inflammation plays a key role in the pathophysiology of heart failure (HF). Prior studies have shown correlation between systemic cytokines and adverse outcomes of HF patients. We hypothesized that inflammatory burden could correlate with the ability of the failing human heart to improve its endogenous function after mechanical unloading induced by left ventricular assist devices (LVAD).
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