Advertisement
The Journal of Heart and Lung Transplantation
International Society for Heart and Lung Transplantation.
Original clinical science| Volume 30, ISSUE 1, P45-53, January 2011

Insurance status is an independent predictor of long-term survival after lung transplantation in the United States

Published:September 28, 2010DOI:https://doi.org/10.1016/j.healun.2010.07.003

      Background

      Socioeconomic factors such as education, health insurance, and race are known to affect health outcomes. The United Network for Organ Sharing (UNOS) database provides a large cohort of lung transplant (LTx) recipients in which to evaluate the effect of insurance on survival.

      Methods

      We retrospectively reviewed UNOS data for 11,385 adult primary LTx patients (1998–2008). Patients were stratified by insurance (private/self-pay, Medicare, Medicaid, and other type). All-cause mortality was examined with Cox proportional hazard regression incorporating 14 variables. The Kaplan-Meier method was used to model survival after LTx.

      Results

      Of 11,385 recipients, 7,100 (62.4%) had private insurance/self-pay; 2,966 (26.1%) had Medicare; 815 (7.2%) had Medicaid; and 504 (4.4%) had other type insurance. During the study, 4,943 patients (43.4%) died. Medicare and Medicaid patients had 7.0% and 8.1% lower 10-year survival than did private insurance/self-pay patients, respectively. Insurance did not affect 30-day, 90-day, or 1-year survival. Medicare and Medicaid patients had decreased survival at 3 years and longer. In multivariable analyses, Medicare (hazard ratio, 1.10; 95% confidence interval, 1.03–1.19) and Medicaid (hazard ratio, 1.29; 95% confidence interval, 1.15–1.45) significantly increased risk of death. When deaths in the first year were excluded, survival differences persisted.

      Conclusions

      This study represents the largest cohort evaluating the effect of insurance on post-LTx survival. Medicare and Medicaid patients have worse survival after LTx compared with private insurance/self-paying patients.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The Journal of Heart and Lung Transplantation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Goldfarb-Rumyantzev A.S.
        • Koford J.K.
        • Baird B.C.
        • et al.
        Role of socioeconomic status in kidney transplant outcome.
        Clin J Am Soc Nephrol. 2006; 1: 313-322
        • Yoo H.Y.
        • Thuluvath P.J.
        Outcome of liver transplantation in adult recipients: influence of neighborhood income, education, and insurance.
        Liver Transpl. 2004; 10: 235-243
        • Kwok J.
        • Langevin S.M.
        • Argiris A.
        • Grandis J.R.
        • Gooding W.E.
        • Taioli E.
        The impact of health insurance status on the survival of patients with head and neck cancer.
        Cancer. 2010; 116: 476-485
        • Curry Jr, W.T.
        • Carter B.S.
        • Barker 2nd, F.G.
        Racial, ethnic, and socioeconomic disparities in patient outcomes after craniotomy for tumor in adult patients in the United States, 1988-2004.
        Neurosurgery. 2010; 66 (discussion 37-8): 427-437
        • Zarzaur B.L.
        • Stair B.R.
        • Magnotti L.J.
        • Croce M.A.
        • Fabian T.C.
        Insurance type is a determinant of 2-year mortality after non-neurologic trauma.
        J Surg Res. 2010; 160: 196-201
        • Lemaire A.
        • Cook C.
        • Tackett S.
        • Mendes D.M.
        • Shortell C.K.
        The impact of race and insurance type on the outcome of endovascular abdominal aortic aneurysm (AAA) repair.
        J Vasc Surg. 2008; 47: 1172-1180
      1. Coverage under Medicare. http://www.medicare.gov/coverage/Search/Results.asp?State=AL|maryland&Coverage=110|Immunosuppressive+Drugs. Accessed: April 12, 2010.

        • Dew M.A.
        • Dimartini A.F.
        • De Vito Dabbs A.
        • et al.
        Adherence to the medical regimen during the first two years after lung transplantation.
        Transplantation. 2008; 85: 193-202
        • Husain A.N.
        • Siddiqui M.T.
        • Holmes E.W.
        • et al.
        Analysis of risk factors for the development of bronchiolitis obliterans syndrome.
        Am J Respir Crit Care Med. 1999; 159: 829-833
        • Sato M.
        • Gutierrez C.
        • Kaneda H.
        • Liu M.
        • Waddell T.K.
        • Keshavjee S.
        The effect of gender combinations on outcome in human lung transplantation: the International Society of Heart and Lung Transplantation Registry experience.
        J Heart Lung Transplant. 2006; 25: 634-637
        • Smits J.M.
        • Mertens B.J.
        • Van Houwelingen H.C.
        • Haverich A.
        • Persijn G.G.
        • Laufer G.
        Predictors of lung transplant survival in Eurotransplant.
        Am J Transplant. 2003; 3: 1400-1406
        • Smits J.M.
        • Vanhaecke J.
        • Haverich A.
        • et al.
        Three-year survival rates for all consecutive heart-only and lung-only transplants performed in Eurotransplant, 1997-1999.
        Clin Transpl. 2003; : 89-100