The Journal of Heart and Lung Transplantation
Volume 29, Issue 12 , Pages 1330-1336 , December 2010

Synergistic effect of antibodies to human leukocyte antigens and defensins in pathogenesis of bronchiolitis obliterans syndrome after human lung transplantation

  • Deepti Saini, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Nataraju Angaswamy, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Venkataswarup Tiriveedhi, MD, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Naohiko Fukami, MD, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Sabarinathan Ramachandran, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Ramsey Hachem, MD

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Elbert Trulock, MD

      Affiliations

    • Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Brian Meyers, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Alexander Patterson, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Thalachallour Mohanakumar, PhD

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, Missouri
    • Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri
    • Corresponding Author InformationReprint requests: Thalachallour Mohanakumar, PhD, Washington University School of Medicine, Department of Surgery, Box 8109-3328 CSRB, 660 S Euclid Ave, St. Louis, MO 63110. Telephone: 314-362-8463. Fax: 314-747-1560

References 

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  19. Slebos DJ, Postma DS, Koeter GH, Van Der Bij W, Boezen M, Kauffman HF. Bronchoalveolar lavage fluid characteristics in acute and chronic lung transplant rejection. J Heart Lung Transplant. 2004;23:532–540
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  25. Nagarkar DR, Wang Q, Shim J, et al. CXCR2 is required for neutrophilic airway inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection. J Immunol. 2009;183:6698–6707
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  27. Girnita AL, Lee TM, McCurry KR, et al. Anti-human leukocyte antigen antibodies, vascular C4d deposition and increased soluble c4d in broncho-alveolar lavage of lung allografts. Transplantation. 2008;86:342–347
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PII: S1053-2498(10)00423-7

doi: 10.1016/j.healun.2010.05.036

The Journal of Heart and Lung Transplantation
Volume 29, Issue 12 , Pages 1330-1336 , December 2010

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