The Journal of Heart and Lung Transplantation
Volume 29, Issue 11 , Pages 1245-1252 , November 2010

Echocardiographic assessment of flow across continuous-flow ventricular assist devices at low speeds

  • Robert S. George, BSc, BM, MRCS

      Affiliations

    • Mechanical Circulatory Support Department, Imperial College, Uxbridge, UK
    • Heart Science Centre, Imperial College, Uxbridge, UK
    • Department of Cardiothoracic Surgery, Leeds General Infirmary, Leeds, UK
    • ,
  • Nikant K. Sabharwal, MRCP, DM

      Affiliations

    • Echocardiography Department, Royal Brompton and Harefield NHS Trust, Uxbridge, UK
    • ,
  • Carole Webb, BSc

      Affiliations

    • Echocardiography Department, Royal Brompton and Harefield NHS Trust, Uxbridge, UK
    • ,
  • Magdi H. Yacoub, FRS

      Affiliations

    • Heart Science Centre, Imperial College, Uxbridge, UK
    • ,
  • Christopher T. Bowles, PhD

      Affiliations

    • Mechanical Circulatory Support Department, Imperial College, Uxbridge, UK
    • ,
  • Michael Hedger, RN

      Affiliations

    • Mechanical Circulatory Support Department, Imperial College, Uxbridge, UK
    • ,
  • Asghar Khaghani, FRCS

      Affiliations

    • Mechanical Circulatory Support Department, Imperial College, Uxbridge, UK
    • ,
  • Emma J. Birks, FRCP, PhD

      Affiliations

    • Mechanical Circulatory Support Department, Imperial College, Uxbridge, UK
    • Heart Science Centre, Imperial College, Uxbridge, UK
    • University of Louisville, Louisville, Kentucky, USA
    • Corresponding Author InformationReprint requests: Emma J. Birks, FRCP, PhD, University of Louisville, 201 Abraham Flexner Way, Suite 1200, Louisville, KY 40222. Telephone: 502-561-2180. Fax: 502-561-2190

References 

  1. Farrar DJ, Lawson JH, Litwak P, et al. Thoratec VAD system as a bridge to heart transplantation. J Heart Lung Transplant. 1990;9:415–422
  2. Frazier OH, Myers TJ. Left ventricular assist system as a bridge to myocardial recovery. Ann Thorac Surg. 1999;68:734–741
  3. Hetzer R, Muller JH, Weng Y, et al. Bridging-to-recovery. Ann Thorac Surg. 2001;71(suppl 3):109–113
  4. Entwistle JW. Long-term mechanical ventricular assistance towards myocardial recovery. Cardiol Clin. 2003;21:75–82
  5. Birks EJ, Tansley PD, Hardy JP, et al. Left ventricular assist device and drug therapy for the reversal of heart failure. N Engl J Med. 2006;355:1873–1884
  6. George RS, Yacoub MH, Tasca G, et al. Hemodynamic and echocardiographic responses to acute interruption of left ventricular assist device support: relevance to assessment of myocardial recovery. J Heart Lung Transplant. 2007;26:967–973
  7. Maybaum S, Stockwell P, Naka Y, et al. Assessment of myocardial recovery in a patient with acute myocarditis supported with a left ventricular assist device: a case report. J Heart Lung Transplant. 2003;22:202–209
  8. Myers T, Frazier O, Mesina H, et al. Hemodynamics and patient safety during pump-off studies of an axial-flow left ventricular assist device. J Heart Lung Transplant. 2006;25:379–383
  9. Slaughter M, Silver M, Farrar D, et al. A new method of monitoring recovery and weaning the Thoratec LVAD. Ann Thorac Surg. 2001;71:215–218
  10. DiGiorgi PL, Smith DL, Naka Y, et al. Retrograde and antegrade flow from pulsatile and non-pulsatile ventricular assist devices. J Heart Lung Transplant. 2004;232:186–192
  11. Feller ED, Sorensen EN, Haddad M, et al. Clinical outcomes are similar in pulsatile and nonpulsatile left ventricular assist device recipients. Ann Thorac Surg. 2007;83:1082–1088
  12. Garcia S, Kandar F, Boyle A, et al. Effects of pulsatile- and continuous-flow left ventricular assist devices on left ventricular unloading. J Heart Lung Transplant. 2008;27:261–267
  13. Haft J, Armstrong W, Dyke DB, et al. Hemodynamic and exercise performance with pulsatile and continuous-flow left ventricular assist devices. Circulation. 2007;116(suppl I):I-8–I-15
  14. Radovancevic B, Vrtovec B, de Kort E, et al. End-organ function in patients on long-term circulatory support with continuous- or pulsatile-flow assist devices. J Heart Lung Transplant. 2007;268:815–818
  15. Yu JJ, Son HS, Lim CH, et al. Comparison of myocardial loading between asynchronous pulsatile and nonpulsatile percutaneous extracorporeal life support. ASAIO J. 2008;54:177–180
  16. Henein M, Birks EJ, Tansley PT, et al. Temporal and spatial changes in left ventricular pattern of flow during continuous assist device “HeartMate II.”. Circulation. 2002;105:2324–2325
  17. Chumnanvej S, Wood MJ, MacGillivray TE, et al. Perioperative echocardiographic examination for ventrivalvar assist device implantation. Anesth Analg. 2007;105:583–601
  18. Slaughter MS, Bartoli CR, Sobieski MA, et al. Intraoperative evaluation of the HeartMate II Flow Estimator. J Heart Lung Transplant. 2009;28:39–43

PII: S1053-2498(10)00356-6

doi: 10.1016/j.healun.2010.05.032

The Journal of Heart and Lung Transplantation
Volume 29, Issue 11 , Pages 1245-1252 , November 2010

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