The Journal of Heart and Lung Transplantation
Volume 29, Issue 9 , Pages 989-996 , September 2010

New prioritization of heart transplant candidates on mechanical circulatory support in an era of severe donor shortage

  • Takeshi Komoda, MD, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Takeshi Komoda, MD, PhD, Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. Telephone: 49-30-4593-2031. Fax: 49-30-4593-2047
  • ,
  • Thorsten Drews, MD
  • ,
  • Roland Hetzer, MD, PhD
  • ,
  • Hans B. Lehmkuhl, MD

References 

  1. Mudge GH, Goldstein S, Addonizio LJ, et al. 24th Bethesda Conference: Cardiac transplantation. Task Force 3: Recipient guidelines/prioritization. J Am Coll Cardiol. 1993;22:21–31
  2. van den Hout WB, Smits JM, Deng MC, et al. The heart-allocation simulation model: a tool for comparison of transplantation allocation policies. Transplantation. 2003;76:1492–1497
  3. Bundesärztekammer . Richtlinien zur Organtransplantation gemäβ §16 Transplantationsgesetz. Duetsches Ärzteblatt. 2000;97:A396–A411
  4. Gesetz über die Spende, Entnahme und Übertragung von Organen (Transplantationsgesetz—TPG) Vom 5. November 1997. Bundesgesetzblatt 1997; Teil I Seite 2631-9.
  5. Tuffs A. Germany introduces new criteria for organ allocation. BMJ. 2000;320:10
  6. Renlund DG, Taylor DO, Kfoury AG, Shaddy RS. New UNOS rules: historical background and implications for transplantation management. J Heart Lung Transplant. 1999;18:1065–1070
  7. Jimenez J, Bennett Edwards L, Higgins R, Bauerlein J, Pham S, Mallon S. Should stable UNOS Status 2 patients be transplanted?. J Heart Lung Transplant. 2005;24:178–183
  8. Krakauer H, Lin MJ, Bailey RC. Projected survival benefit as criterion for listing and organ allocation in heart transplantation. J Heart Lung Transplant. 2005;24:680–689
  9. Mokadam NA, Ewald GA, Damiano RJ, Moazami N. Deterioration and mortality among patients with United Network for Organ Sharing status 2 heart disease: caution must be exercised in diverting organs. J Thorac Cardiovasc Surg. 2006;131:925–926
  10. Lietz K, Miller LW. Improved survival of patients with end-stage heart failure listed for heart transplantation: analysis of organ procurement and transplantation network/U.S. United Network of Organ Sharing data, 1990 to 2005. J Am Coll Cardiol. 2007;50:1282–1290
  11. Komoda T, Hetzer R, Lehmkuhl HB. Influence of new Eurotransplant heart allocation policy on outcome of heart transplant candidates in Germany. J Heart Lung Transplant. 2008;27:1108–1114
  12. Komoda T, Hetzer R, Lehmkuhl HB. Destiny of candidates for heart transplantation in the Eurotransplant heart allocation system. Eur J Cardiothorac Surg. 2008;34:301–306
  13. Frazier OH, Rose EA, Oz MC, et al. Multicenter clinical evaluation of the heartmate; vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186–1195
  14. Gammie JS, Edwards LB, Griffith BP, Pierson RN, Tsao L. Optimal timing of cardiac transplantation after ventricular assist device implantation. J Thorac Cardiovasc Surg. 2004;127:1789–1799
  15. Dang NC, Topkara VK, Kim BT, Mercando ML, Kay J, Naka Y. Clinical outcomes in patients with chronic congestive heart failure who undergo left ventricular assist device implantation. J Thorac Cardiovasc Surg. 2005;130:1302–1309
  16. Deng MC, Edwards LB, Hertz MI, et al. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: third annual report–2005. J Heart Lung Transplant. 2005;24:1182–1187
  17. Miller LW, Pagani FD, Russell SD, et al. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med. 2007;357:885–896
  18. McCarthy PM, Smedira NO, Vargo RL. One hundred patients with the HeartMate left ventricular assist device: evolving concepts and technology. J Thorac Cardiovasc Surg. 1998;115:904–912
  19. El-Banayosy A, Deng M, Loisance DY, et al. The European experience of Novacor left ventricular assist (LVAS) therapy as a bridge to transplant: a retrospective multi-centre study. Eur J Cardiothorac Surg. 1999;15:835–841
  20. Strüber M, Sander K, Lahpor J, et al. HeartMate II left ventricular assist device; early European experience. Eur J Cardiothorac Surg. 2008;34:289–294
  21. Holman WL, Kormos RL, Naftel DC, et al. Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. J Heart Lung Transplant. 2009;28:44–50
  22. Poston RS, Husain S, Sorce D, et al. LVAD bloodstream infections: therapeutic rationale for transplantation after LVAD infection. J Heart Lung Transplant. 2003;22:914–921
  23. Simon D, Fischer S, Grossman A, et al. Left ventricular assist device-related infection: treatment and outcome. Clin Infect Dis. 2005;40:1108–1115
  24. Burnett CM, Duncan JM, Frazier OH, Sweeney MS, Vega JD, Radovancevic B. Improved multiorgan function after prolonged univentricular support. Ann Thorac Surg. 1993;55:65–71
  25. Russell SD, Rogers JG, Milano CA, et al. Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist device. Circulation. 2009;120:2352–2357
  26. Vega JD, Poindexter SM, Radovancevic B, et al. Nutritional assessment of patients with extended left ventricular assist device support. ASAIO Trans. 1990;36:M555–M558
  27. Dang NC, Topkara VK, Kim BT, Lee BJ, Remoli R, Naka Y. Nutritional status in patients on left ventricular assist device support. J Thorac Cardiovasc Surg. 2005;130:e3–e4

PII: S1053-2498(10)00282-2

doi: 10.1016/j.healun.2010.05.001

The Journal of Heart and Lung Transplantation
Volume 29, Issue 9 , Pages 989-996 , September 2010