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The Journal of Heart and Lung Transplantation
Volume 29, Issue 6
, Pages 603-609
, June 2010
Reversal of impaired myocardial β-adrenergic receptor signaling by continuous-flow left ventricular assist device support
References
- Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med. 1982;307:205–211
- . Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure. Cardiovasc Res. 1995;30:570–584
- Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem. 1993;268:23735–23738
- Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. Circ Res. 1994;74:206–213
- Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation. 1993;87:454–463
- Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer. Proc Natl Acad Sci U S A. 1997;94:12100–12105
- Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure. Circulation. 2009;119:89–98
- G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure. Circ Res. 2008;103:413–422
- In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. Circulation. 1999;100:648–653
- Restoration of myocardial β-adrenergic receptor signaling following left ventricular assist device support. J Thorac Cardiovasc Surg. 2006;131:975–980
- Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure. Circulation. 2000;102:2713–2719
- Effect of the implantable left ventricular assist device on neuroendocrine activation in heart failure. Circulation. 1995;92:II191–II195
- Myocardial β1-adrenergic receptor polymorphisms affect functional recovery following ischemic injury. Am J Physiol Heart Circ Physiol. 2006;290:H1427–H1432
- . A highly sensitive adenylate cyclase assay. Anal Biochem. 1974;58:541–548
- Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure. Eur Heart J. 2005;26:1752–1758
- . Seven-transmembrane-spanning receptors and heart function. Nature. 2002;415:206–212
- Phosphorylation and desensitization of the human β1-adrenergic receptor: involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase. J Biol Chem. 1995;270:17953–17961
- The binding site for the βγ subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J Biol Chem. 1993;268:8256–8260
- Hybrid transgenic mice reveal in vivo specificities of G protein-coupled receptor kinases in the heart. Circ Res. 2000;86:43–50
- Cardiac function in mice overexpressing the β-adrenergic receptor kinase or a βARK inhibitor. Science. 1995;268:1350–1353
- Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci U S A. 2000;97:5428–5433
- Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci U S A. 1998;95:7000–7005
- . Targeting myocardial β-adrenergic receptor signaling and calcium cycling for heart failure gene therapy. J Cardiac Fail. 2007;13:401–414
- Ex Vivo adenovirus-mediated gene transfer to the adult rat heart. J Thorac Cardiovasc Surg. 1998;115:623–630
- . Beta-adrenoceptors in cardiac disease. Pharmac Ther. 1993;60:405–430
- Hemodynamic and exercise performance with pulsatile and continuous-flow left ventricular assist devices. Circulation. 2007;116(suppl I):8–15
- Cellular and hemodynamic responses of failing myocardium to continuous flow mechanical circulatory support using the DeBakey-Noon left ventricular assist device: a comparative analysis with pulsatile-type devices. J Heart Lung Transplant. 2005;24:566–575
PII: S1053-2498(10)00042-2
doi: 10.1016/j.healun.2010.01.010
© 2010 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Heart and Lung Transplantation
Volume 29, Issue 6
, Pages 603-609
, June 2010
