The Journal of Heart and Lung Transplantation
Volume 29, Issue 6 , Pages 710-711 , June 2010

Reversible severe synovitis associated with everolimus

  • Tomoko S. Kato, MD, PhD

      Affiliations

    • Department of Cardiovascular Medicine, National Cardiovascular Center, Osaka, Japan
    • Department of Organ Transplantation, National Cardiovascular Center, Osaka, Japan
  • ,
  • Taro Sasaoka, MD

      Affiliations

    • Department of Cardiovascular Medicine, National Cardiovascular Center, Osaka, Japan
  • ,
  • Kyoichi Wada, PhD

      Affiliations

    • Department of Pharmacology, National Cardiovascular Center, Osaka, Japan
  • ,
  • Takeshi Nakatani, MD, PhD

      Affiliations

    • Department of Organ Transplantation, National Cardiovascular Center, Osaka, Japan
  • ,
  • Kazuo Komamura, MD, PhD

      Affiliations

    • Department of Cardiovascular Medicine, National Cardiovascular Center, Osaka, Japan
    • Department of Organ Transplantation, National Cardiovascular Center, Osaka, Japan

References 

  1. Rothenburger M, Zuckermann A, Bara C, et al. Recommendations for the use of everolimus (Certican) in heart transplantation: results from the second German–Austrian Certican Consensus Conference. J Heart Lung Transplant. 2007;26:305–311
  2. Morelon E, Stern M, Israel-Biet D, et al. Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients. Transplantation. 2001;72:787–790
  3. Champion L, Stern M, Israel-Biet D, et al. Sirolimus-associated pneumonitis: 24 cases in renal transplant recipients. Ann Intern Med. 2006;144:505–509
  4. Yoon KH. Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option. Ann NY Acad Sci. 2009;1173:752–756
  5. Bruyn GA, Tate G, Caeiro F, et al. Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomized, placebo-controlled, parallel-group, proof-of-concept study. Ann Rheum Dis. 2008;67:1090–1095

PII: S1053-2498(10)00033-1

doi: 10.1016/j.healun.2010.01.001

The Journal of Heart and Lung Transplantation
Volume 29, Issue 6 , Pages 710-711 , June 2010