The Journal of Heart and Lung Transplantation
Volume 29, Issue 6 , Pages 687-691 , June 2010

Optimization of axial-pump pressure sensitivity for a continuous-flow total artificial heart

  • O.H. Frazier, MD

      Affiliations

    • Department of Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas
    • Corresponding Author InformationReprint requests: O.H. Frazier, MD, Department of Cardiovascular Surgery, Texas Heart Institute, P.O. Box 20345, MC 3-147, Houston, TX 77225-0345. Telephone: 832-355-3000. Fax: 832-355-6798
    • ,
  • Hassan A. Khalil, BS

      Affiliations

    • Department of Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas
    • ,
  • Robert J. Benkowski, BS

      Affiliations

    • MicroMed Technology, Inc., Houston, Texas
    • ,
  • William E. Cohn, MD

      Affiliations

    • Department of Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas

References 

  1. Garcia S, Kandar F, Boyle A, et al. Effects of pulsatile- and continuous-flow left ventricular assist devices on left ventricular unloading. J Heart Lung Transplant. 2008;27:261–267
  2. Frazier OH, Tuzun E, Cohn W, et al. Total heart replacement with dual centrifugal ventricular assist devices. ASAIO J. 2005;51:224–229
  3. Frazier OH, Tuzun E, Cohn WE, et al. Total heart replacement using dual intracorporeal continuous-flow pumps in a chronic bovine model: a feasibility study. ASAIO J. 2006;52:145–149
  4. Khalil HA, Cohn WE, Metcalfe RW, et al. Preload sensitivity of the Jarvik 2000 and HeartMate II left ventricular assist devices. ASAIO J. 2008;54:245–248
  5. Saxton GA, Andrews CB. An ideal heart pump with hydrodynamic characteristics analogous to the mammalian heart. Trans Am Soc Artif Intern Organs. 1960;6:288–291
  6. Akimoto T, Yamazaki K, Litwak P, et al. Rotary blood pump flow spontaneously increases during exercise under constant pump speed: results of a chronic study. Artif Organs. 1999;23:797–801
  7. Khalil HA, Kerr DT, Franchek MA, et al. Continuous flow total artificial heart: modeling and feedback control in a mock circulatory system. ASAIO J. 2008;54:249–255
  8. Guyton AC, Hall JE. Textbook of medical physiology. 10th ed.. Philadelphia: Saunders; 2000;
  9. Gemmato CJ, Forrester MD, Myers TJ, et al. Thirty-five years of mechanical circulatory support at the Texas Heart Institute: an updated overview. Tex Heart Inst J. 2005;32:168–177

PII: S1053-2498(09)01538-1

doi: 10.1016/j.healun.2009.12.017

The Journal of Heart and Lung Transplantation
Volume 29, Issue 6 , Pages 687-691 , June 2010

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