The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 491-496 , May 2010

An indictment of the STICH trial: “True, true, and unrelated”

  • John Conte, MD

      Affiliations

    • Corresponding Author InformationReprint requests: John Conte, MD, Division of Cardiac Surgery, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287-4618. Telephone: 410-955-1753. Fax: 410-955-3809

References 

  1. Jones RH, Velazquez EJ, Michler RE, et al. Coronary bypass surgery with or without surgical ventricular reconstruction. N Engl J Med. 2009;360:1705–1717
  2. The North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991;325:445–453
  3. Gaudron P, Eilles C, Kugler I, et al. Progressive left ventricular dysfunction and remodeling after myocardial infarction: potential mechanisms and early predictors. Circulation. 1993;87:755–763
  4. Di Donato M, Sabatier M, Toso A, et al. Regional myocardial performance of non-ischemic zones remote from anterior wall left ventricular aneurysm. Eur Heart J. 1995;16:1285–1292
  5. Fauchier L, Marie O, Cassett D, et al. Intraventriacular and interventriculaar dyssynchrony in idiopathic dilated cardiomyopathy: a prognostic study with Fournier phase analysis of radionucleotide angioscintigraphy. Am Coll Cardiol. 2002;40:2022–2030
  6. Di Donato M, Toso A, Dor V, et al. Surgical ventricular restoration improves mechanical intraventricular dyssynchrony in ischemic cardiomyopathy. Circulation. 2004;109:2536–2543
  7. Gheorghiade M, Bonow RO. Chronic heart failure in the United States: a manifestation of coronary artery disease. Circulation. 1998;97:282–289
  8. White HD, Norris RM, Brown PW, et al. Left ventricular end systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation. 1987;76:44–51
  9. Levy D, Kenchaiah S, Larson MG, et al. Long-term trends in the incidence of and survival with heart failure. N Engl J Med. 2002;347:1397–1402
  10. Migrin RQ, Young JB, Ellis SG, et al. End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality: the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I Angiographic Investigators. Circulation. 1997;96:116–121
  11. Allman KC, Shaw LJ, Hachamovitch R, et al. Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis. J Am Coll Cardiol. 2002;39:1151–1158
  12. Senior R, Lahiri A, Kaul S. Effect of revascularization on left ventricular remodeling in patients with heart failure from severe chronic ischemic left ventricular dysfunction. Am J Cardiol. 2001;88:624–629
  13. Bax JJ, Schinkel AF, Boersma E, et al. Extensive left ventricular remodeling does not allow viable myocardium to improve in left ventricular ejection fraction after revascularization and is associated with worse long term prognosis. Circulation. 2004;110:II-18-22
  14. Cooley DA, Collins HA, Hall GA, et al. Ventricular aneurysm after myocardial infarction: surgical excision with use of temporary cardiopulmonary bypass. JAMA. 1958;167:557
  15. Jatene AD. Left ventricular aneurysmectomy: resection or reconstruction?. J Thorac Cardiovasc Surg. 1985;89:321–331
  16. Fontan F. Transplantation of knowledge. J Thorac Cardiovasc Surg. 1990;99:387–395
  17. Dor V, Kreitmann P, Jourdan J. Interest of “physiological” closure of left ventricle after resection and endocardiectomy for aneurysm or akinetic zone comparison with classical technique about a series of 209 left ventricular resections [abstract]. J Cardiovascular Surg. 1985;26:73
  18. Cox JL. Surgical management of left ventricular aneurysms: a clarification of the similarities and differences between the Jatene and Dor techniques. Semin Thorac Cardiovasc Surg. 1997;9:131–138
  19. Caldiera C, McCarthy PM. A simple method of left ventricular reconstruction without patch for ischemic cardiomyopathy. Ann Thorac Surg. 2001;72:2148–2149
  20. Mickleborough LL. Tech Card. Thorac Surg. 1997;2:118–131
  21. Conte JV. Surgical ventricular restoration: technique and outcomes. Congest Heart Fail. 2004;10:248–251
  22. Natori S, Conte JV, Lima JAC, et al. Magnetic resonance imaging evaluation of surgical ventricular restoration. Ann Thorac Surg. 2005;80:743
  23. Dor V. Left ventricular reconstruction: the aim and the reality after twenty years. J Thorac Cardiovasc Surg. 2004;128:17–20
  24. Menicanti L, Castelvecchio S, Ranucci M, et al. Surgical therapy for ischemic heart failure: single center experience with surgical anterior ventricular restoration. J Thorac Cardiovasc Surg. 2007;134:433–441
  25. Athanasuleas CL, Buckberg GD, Stanley AH, et al. RESTORE group surgical ventricular restoration in the treatment of congestive heart failure due to post-infarction ventricular dilation. J Am Coll Cardiol. 2004;44:1439–1442
  26. Schreuder JJ, Castiglioni A, Maisano F, et al. Acute decrease of left ventricular mechanical dyssynchrony and improvement of contractile state and energy efficiency after left ventricular restoration. J Thorac Cardiovasc Surg. 2005;129:138–145
  27. Castelvecchio S, Menicanti L, Ranucci M, et al. Impact of surgical ventricular restoration on diastolic function: implications of shape and residual ventricular size. Ann Thorac Surg. 2008;86:1849–1854
  28. Di Donato M, Toso A, Dor V, et al. Surgical ventricular restoration improves mechanical ventricular dyssynchrony in ischemic cardiomyopathy. Circulation. 2004;109:2536–2543
  29. Setser RM, Smedira NG, Lieber ML, et al. Left ventricular torsional mechanics after left ventricular reconstruction surgery for ischemic cardiomyopathy. J Thorac Cardiovasc Surg. 2007;134:888–896
  30. Schenk S, McCarthy PM, Starling RC, et al. Neurohormonal response to left ventricular reduction surgery in ischemic cardiomyopathy. J Thorac Cardiovasc Surg. 2003;128:38–43
  31. Tulner SA, Steendijk P, Klautz RJ, et al. Clinical efficacy of surgical heart failure therapy by ventricular restoration and restrictive mitral annuloplasty. J Card Fail. 2007;13:178–183
  32. Di Donato M, Sabatier M, Dor V, et al. Surgical ventricular restoration in patients with post-infarction coronary artery disease: effectiveness on spontaneous and inducible ventricular tachycardia. Semin Thorac Cardiovasc Surg. 2001;13:480–485
  33. Di Donato M, Sabatier V, Dor G, et al. Ventricular arrhythmias after LV remodelling: surgical ventricular restoration or ICD?. Heart Fail Rev. 2004;9:299–306
  34. William JA, Weiss ES, Patel ND, et al. Surgical ventricular restoration versus cardiac transplantation: a comparison of cost, outcomes and survival. J Card Fail. 2008;7:547–554
  35. Elefteriades JA, Edwards R. Coronary bypass in left heart failure. Semin Thorac Cardiovasc Surg. 2002;14:125–132
  36. STICH trial protocol. http://clinicaltrials.gov/archive/NCT00023595/2005_06_23
  37. Doenst T, Velazquez EJ, Beyersdorf F, et al. To STICH or not to STICH: we know the answer, but do we understand the question?. J Thorac Cardiovasc Surg. 2005;129:246–249http://clinicaltrials.gov/show/NCT00023595
  38. Menicanti L, Di Donato M. Surgical ventricular reconstruction and mitral regurgitation: what have we learned from 10 years of experience?. Semin Thorac Cardiovasc Surg. 2001;13:496–503
  39. theheart.org http://www.theheart.org/editorial-program/956041.doaccessed May 12, 2009
  40. American College of Cardiology. http://www.acc.org/media/acc_scientific_session_09/press/sunday/ACC09Mark_930.pdfaccessed March 29, 2009
  41. Eisen HJ. Surgical ventricular reconstruction for heart failure. N Engl J Med. 2009;360:1781–1784
  42. Di Donato M, Castelvecchio S, Kukulski T, et al. Surgical ventricular restoration: left ventricular shape influence on cardiac function, clinical status, and survival. Ann Thorac Surg. 2009;87:455–461
  43. Suma H, Tanabe H, Uejima T, et al. Surgical ventricular restoration combined with mitral valve procedure for endstage ischemic cardiomyopathy. Eur J Cardiothorac Surg. 2009;36:280–284
  44. Dor V, Civaia F, Alexandrescu C, et al. The post-myocardial infarction scarred ventricle and congestive heart failure: the preeminence of magnetic resonance imaging for preoperative, intraoperative, and postoperative assessment. J Thorac Cardiovasc Surg. 2008;136:1405–1412
  45. O'Neill JO, Starling RC, McCarthy PM, et al. The impact of left ventricular reconstruction on survival in patients with ischemic cardiomyopathy. Eur J Cardiothorac Surg. 2006;30:753–759
  46. Adams JD, Fedoruk LM, Tache-Leon CA, et al. Does preoperative ejection fraction predict operative mortality with left ventricular restoration?. Ann Thorac Surg. 2006;82:1715–1719
  47. Schreuder JJ, Castiglioni A, Maisano F, et al. Acute decrease of left ventricular mechanical dyssynchrony and improvement of contractile state and energy efficiency after left ventricular restoration. J Thorac Cardiovasc Surg. 2005;129:138–145
  48. Tulner SA, Steendijk P, Klautz RJ, et al. Surgical ventricular restoration in patients with ischemic dilated cardiomyopathy: evaluation of systolic and diastolic ventricular function, wall stress, dyssynchrony, and mechanical efficiency by pressure–volume loops. J Thorac Cardiovasc Surg. 2006;132:610–620
  49. Yamaguchi A, Adachi H, Kawahito K, et al. Left ventricular reconstruction benefits patients with dilated ischemic cardiomyopathy. Ann Thorac Surg. 2005;79:456–461
  50. Mickleborough LL, Merchant N, Ivanov J, et al. Left ventricular reconstruction: early and late results. J Thorac Cardiovasc Surg. 2004;128:27–37

PII: S1053-2498(09)01531-9

doi: 10.1016/j.healun.2009.12.010

The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 491-496 , May 2010