The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 538-543 , May 2010

Gal knockout pig pericardium: New source of material for heart valve bioprostheses

  • Nermine Lila, DVM, PhD

      Affiliations

    • University Paris Descartes, Laboratory of Biosurgical Researches, Georges Pompidou Hospital, Paris, France
    • Corresponding Author InformationReprint requests: Nermine Lila, DVM, PhD, University Paris Descartes, Laboratory of Biosurgical Researches, Georges Pompidou Hospital, 56 rue Leblanc 75015 Paris, France. Telephone: 33-1-56-09-59-07. Fax: 33-1-56-09-59-03
    • ,
  • Christopher G.A. McGregor, MD, PhD

      Affiliations

    • William J. von Liebig Transplant Center, Mayo Clinic Rochester, Rochester, Minnesota, USA
    • ,
  • Sophie Carpentier, PhD

      Affiliations

    • University Paris Descartes, Laboratory of Biosurgical Researches, Georges Pompidou Hospital, Paris, France
    • ,
  • Jeanne Rancic

      Affiliations

    • University Paris Descartes, Laboratory of Biosurgical Researches, Georges Pompidou Hospital, Paris, France
    • ,
  • Guerard W. Byrne, PhD

      Affiliations

    • William J. von Liebig Transplant Center, Mayo Clinic Rochester, Rochester, Minnesota, USA
    • ,
  • Alain Carpentier, MD, PhD

      Affiliations

    • University Paris Descartes, Laboratory of Biosurgical Researches, Georges Pompidou Hospital, Paris, France
    • Assistance Publique Hôpitaux de Paris, Department of Cardiovascular Surgery and Organ Transplantation, Georges Pompidou Hospital, Paris, France

References 

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  25. Nottle MB, Beebe LF, Harrison SJ, et al. Production of homozygous alpha-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer. Xenotransplantation. 2007;14:339–344
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  28. McGregor CGA, Lila N, Vlasin M, et al. Reduced calcification of glutaraldehyde treated pericardium from cloned Gal knockout pigs: effects of anti-gal antibody in the rat model. Presented at the fifth biennial meeting of the Society for Heart Valve Disease, June 2009, Berlin, Germany.
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PII: S1053-2498(09)00819-5

doi: 10.1016/j.healun.2009.10.007

The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 538-543 , May 2010

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