The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 596-598 , May 2010

Lung transplantation under a tacrolimus/mycophenolate mofetil-based immunosuppressive regimen results in low titers of HLA and MICA IgG antibodies which are not related to development of BOS

  • Annelieke W.M. Paantjens, MSc

      Affiliations

    • Department of Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands
    • ,
  • Ed A. van de Graaf, MD, PhD

      Affiliations

    • Department of Respiratory Medicine, University Medical Centre, Utrecht, Utrecht, The Netherlands
    • ,
  • Walter G.J. van Ginkel, BSc

      Affiliations

    • Department of Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands
    • ,
  • Jules M.M. van den Bosch, MD, PhD

      Affiliations

    • Department of Pulmonary Disease, St Antonius Hospital, Nieuwegein, The Netherlands
    • ,
  • Henny G. Otten, PhD

      Affiliations

    • Department of Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands

References 

  1. Palmer SM, Davis RD, Hadjiliadis D. Development of an antibody specific to major histocompatibility antigens detectable by flow cytometry after lung transplant is associated with bronchiolitis obliterans syndrome. Transplantation. 2002;74:799–804
  2. Schulman LL, Ho EK, Reed EF, et al. Immunologic monitoring in lung allograft recipients. Transplantation. 1996;61:252–257
  3. Terasaki PI, Ozawa M. Predicting kidney graft failure by HLA antibodies: a prospective trial. Am J Transplant. 2004;4:438–443
  4. Amico P, Honger G, Mayr M, Steiger J, Hopfer H, Schaub S. Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads. Transplantation. 2009;87:1681–1688
  5. Higgins R, Lowe D, Hathaway M. Rises and falls in donor-specific and third-party HLA antibody levels after antibody incompatible transplantation. Transplantation. 2009;87:882–888

PII: S1053-2498(09)00799-2

doi: 10.1016/j.healun.2009.10.004

The Journal of Heart and Lung Transplantation
Volume 29, Issue 5 , Pages 596-598 , May 2010

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