The Journal of Heart and Lung Transplantation
Volume 29, Issue 4 , Pages 424-431 , April 2010

The efficacy of photopheresis for bronchiolitis obliterans syndrome after lung transplantation

  • Matthew R. Morrell, MD

      Affiliations

    • Division of Pulmonary & Critical Care Medicine, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri
    • Corresponding Author InformationReprint requests: Matthew R. Morrell, MD, Division of Pulmonary & Critical Care Medicine, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8052, St. Louis, MO 63110. Telephone: 314-454-8766. Fax: 314-454-7956
    • ,
  • George J. Despotis, MD

      Affiliations

    • Department of Pathology, Immunology and Anesthesiology, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri
    • ,
  • Douglas M. Lublin, MD, PhD

      Affiliations

    • Department of Pathology and Immunology, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri
    • ,
  • George A. Patterson, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri
    • ,
  • Elbert P. Trulock, MD

      Affiliations

    • Division of Pulmonary & Critical Care Medicine, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri
    • ,
  • Ramsey R. Hachem, MD

      Affiliations

    • Division of Pulmonary & Critical Care Medicine, Washington University School of Medicine/Barnes-Jewish Hospital, St. Louis, Missouri

References 

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  5. Shitrit D, Bendayan D, Gidon S, Saute J, Bakal I, Kramer MR. Long-term azithromycin use for treatment of bronchiolitis obliterans syndrome in lung transplant recipients. J Heart Lung Transplant. 2005;24:1440–1443
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  12. Szczepiorkowski ZM, Bandarenko N, Kim HC, et al. Guidelines on the use of therapeutic apheresis in clinical practice: evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. J Clin Apher. 2007;22:106–175
  13. Andreu G, Achkar A, Couetil JP, et al. Extracorporeal photochemotherapy treatment for acute lung rejection episode. J Heart Lung Transplant. 1995;14:793–796
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  16. Salerno CT, Park SJ, Kreykes NS, et al. Adjuvant treatment of refractory lung transplant rejection with extracorporeal photopheresis. J Thorac Cardiovasc Surg. 1999;117:1063–1069
  17. Villanueva J, Bhorade SM, Robinson JA, Husain AN, Garrity ER. Extracorporeal photopheresis for the treatment of lung allograft rejection. Ann Transplant. 2000;5:44–47
  18. Benden C, Speich R, Hofbauer GF, et al. Extracorporeal photopheresis after lung transplantation: a 10-year single-center experience. Transplantation. 2008;86:1625–1627
  19. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26:319–338
  20. Estenne M, Maurer JR, Boehler A, et al. Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant. 2002;21:297–310
  21. Yoo EK, Rook AH, Elenitsas R, Gasparro FP, Vowels BR. Apoptosis induction of ultraviolet light A and photochemotherapy in cutaneous T-cell lymphomas: relevance to mechanism of therapeutic action. J Invest Dermatol. 1996;107:235–242
  22. Suchin KR, Cassin M, Washko R, et al. Extracorporeal photochemotherapy does not suppress T- or B-cell response to novel or recall antigens. J Am Acad Dermatol. 1999;41:980–986
  23. Lamioni A, Parisi F, Isacchi F, et al. The immunological effects of extracorporeal photopheresis unraveled: induction of tolerogenic dendritic cells in vitro and regulatory T cells in vivo. Transplant. 2005;79:846–850
  24. Ferguson TA, Herndon J, Elzey B, Griffith TS, Schoenberger S, Green DR. Uptake of apoptotic antigen-couples cells by lymphoid dendritic cells and cross-priming of CD8(+) T cells produce active immune unresponsiveness. J Immunol. 2002;168:5589–5595
  25. Meloni F, Cascina A, Miserere S, Perotti C, Vitulo P, Fietta AM. Peripheral CD+CD25+ TREG cell counts and the response to extracorporeal photopheresis in lung transplant recipients. Transplant Proc. 2007;39:213–217
  26. Tokura Y, Seo N, Yagi H, et al. Treatment of T lymphocytes with 8-methoxy-psoralen plus ultraviolet A induces transient but biologically active Th1-skewing cytokine production. J Invest Dermatol. 1999;113:202–208
  27. Vowels BR, Cassin M, Boufal MH, Walsha LJ, Rook AH. Extracorporeal photochemotherapy induces the production of tumor necrosis factor-alpha by monocytes: implications for the treatment of cutaneous T-cell lymphomas and systemic sclerosis. J Invest Dermatol. 1992;98:686–692
  28. Bladon J, Taylor PC. Lymphocytes treated by extracorporeal photopheresis can down-regulate cytokine production in untreated monocytes. Photodermatol Photoimmunol Photomed. 2005;21:293–302
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  30. Lama VN, Murray S, Lonigro RJ, et al. Course of FEV after onset of bronchiolitis obliterans syndrome in lung transplant recipients. Am J Respir Crit Care Med. 2007;175:1192–1198
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  32. Heng D, Sharples LD, McNeil K, Stewart S, Wreghitt T, Wallwork J. Bronchiolitis obliterans syndrome: incidence, natural history, prognosis, and risk factors. J Heart Lung Transplant. 1998;17:1255–1263

PII: S1053-2498(09)00717-7

doi: 10.1016/j.healun.2009.08.029

The Journal of Heart and Lung Transplantation
Volume 29, Issue 4 , Pages 424-431 , April 2010

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