The Journal of Heart and Lung Transplantation
Volume 29, Issue 3 , Pages 291-298 , March 2010

Interactions among donor characteristics influence post-transplant survival: A multi-institutional analysis

  • Josef Stehlik, MD, MPH

      Affiliations

    • Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah
    • Corresponding Author InformationReprint requests: Josef Stehlik, MD, MPH, University of Utah Health Sciences, VA Salt Lake City Health Care System, Intermountain Medical Center, Cardiology Section (111CT)/Heart Failure and Transplant Office, 50 N Medical Dr, 4A100 SOM, Salt Lake City, UT 84132. Telephone: 801-581-7715. Fax: 801-584-2532
    • ,
  • David S. Feldman, MD, PhD

      Affiliations

    • Ohio State University, Columbus, Ohio
    • ,
  • Robert N. Brown, MS

      Affiliations

    • University of Alabama, Birmingham, Alabama
    • ,
  • Adrian B. VanBakel, MD

      Affiliations

    • Medical University of South Carolina, Charleston, South Carolina
    • ,
  • Stewart D. Russel, MD

      Affiliations

    • Johns Hopkins University, Baltimore, Maryland
    • ,
  • Gregory A. Ewald, MD

      Affiliations

    • Washington University School of Medicine, St. Louis, Missouri
    • ,
  • Mary E. Hagan, ANP

      Affiliations

    • Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah
    • ,
  • Jan Folsom

      Affiliations

    • Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, Utah
    • ,
  • James K. Kirklin, MD

      Affiliations

    • University of Alabama, Birmingham, Alabama
    • ,
  • Cardiac Transplant Research Database Group

References 

  1. Taylor DO, Edwards LB, Boucek MM, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult heart transplantation report—2006. J Heart Lung Transplant. 2006;25:869–879
  2. Taylor DO, Edwards LB, Boucek MM, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report—2007. J Heart Lung Transplant. 2007;26:769–781
  3. Taylor DO, Edwards LB, Aurora P, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-fifth official adult heart transplant report—2008. J Heart Lung Transplant. 2008;27:943–956
  4. Rodeheffer RJ, Naftel DC, Stevenson LW, et al. Cardiac Transplant Research Database Group Secular trends in cardiac transplant recipient and donor management in the United States, 1990 to 1994 (A multi-institutional study). Circulation. 1996;94:2883–2889
  5. Kfoury AG, Stehlik J, Renlund DG, et al. Impact of repetitive episodes of antibody-mediated or cellular rejection on cardiovascular mortality in cardiac transplant recipients: defining rejection patterns. J Heart Lung Transplant. 2006;25:1277–1282
  6. Kirklin JK, Brown RN, Huang ST, et al. Rejection with hemodynamic compromise: objective evidence for efficacy of photopheresis. J Heart Lung Transplant. 2006;25:283–288
  7. Grady KL, Naftel D, Pamboukian SV, et al. Post-operative obesity and cachexia are risk factors for morbidity and mortality after heart transplant: multi-institutional study of post-operative weight change. J Heart Lung Transplant. 2005;24:1424–1430
  8. Young JB, Hauptman PJ, Naftel DC, et al. Determinants of early graft failure following cardiac transplantation, a 10-year, multi-institutional, multivariable analysis. J Heart Lung Transplant. 2001;20:212
  9. Felker GM, Milano CA, Yager JE, et al. Outcomes with an alternate list strategy for heart transplantation. J Heart Lung Transplant. 2005;24:1781–1786
  10. Laks H, Scholl FG, Drinkwater DC, et al. The alternate recipient list for heart transplantation: does it work?. J Heart Lung Transplant. 1997;16:735–742
  11. Lima B, Rajagopal K, Petersen RP, et al. Marginal cardiac allografts do not have increased primary graft dysfunction in alternate list transplantation. Circulation. 2006;114(1 suppl):I27–I32
  12. Patel J, Kobashigawa JA. Cardiac transplantation: the alternate list and expansion of the donor pool. Curr Opin Cardiol. 2004;19:162–165
  13. Pflugfelder PW, Singh NR, McKenzie FN, et al. Extending cardiac allograft ischemic time and donor age: effect on survival and long-term cardiac function. J Heart Lung Transplant. 1991;10:394–400
  14. Wittwer T, Wahlers T. Marginal donor grafts in heart transplantation: lessons learned from 25 years of experience. Transpl Int. 2008;21:113–125
  15. Young JB, Naftel DC, Bourge RC, et al. The Cardiac Transplant Research Database Group Matching the heart donor and heart transplant recipient (Clues for successful expansion of the donor pool: a multivariable, multiinstitutional report). J Heart Lung Transplant. 1994;13:353–364discussion 364–5
  16. Wolfe RA, LaPorte FB, Rodgers AM, Roys EC, Fant G, Leichtman AB. Developing organ offer and acceptance measures: when “good” organs are turned down. Am J Transplant. 2007;7:1404–1411
  17. Marelli D, Laks H, Fazio D, Moore S, Moriguchi J, Kobashigawa J. The use of donor hearts with left ventricular hypertrophy. J Heart Lung Transplant. 2000;19:496–503
  18. Kuppahally SS, Valantine HA, Weisshaar D, et al. Outcome in cardiac recipients of donor hearts with increased left ventricular wall thickness. Am J Transplant. 2007;7:2388–2395
  19. Del Rizzo DF, Menkis AH, Pflugfelder PW, et al. The role of donor age and ischemic time on survival following orthotopic heart transplantation. J Heart Lung Transplant. 1999;18:310–319
  20. Topkara VK, Cheema FH, Kesavaramanujam S, et al. Effect of donor age on long-term survival following cardiac transplantation. J Cardiac Surg. 2006;21:125–129
  21. Chin C, Naftel DC, Singh TP, et al. Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. J Heart Lung Transplant. 2004;23:178–185
  22. Hiemann NE, Knosalla C, Wellnhofer E, Lehmkuhl HB, Hetzer R, Meyer R. Beneficial effect of female gender on long-term survival after heart transplantation. Transplantation. 2008;86:348–356
  23. Tjang YS, van der Heijden GJ, Tenderich G, Grobbee DE, Korfer R. Survival analysis in heart transplantation: results from an analysis of 1290 cases in a single center. Eur J Cardiothorac Surg. 2008;33:856–861
  24. Al-Khaldi A, Oyer PE, Robbins RC. Outcome analysis of donor gender in heart transplantation. J Heart Lung Transplant. 2006;25:461–468
  25. Yamani MH, Erinc SK, McNeill A, et al. The impact of donor gender on cardiac peri-transplantation ischemia injury. J Heart Lung Transplant. 2005;24:1741–1744
  26. Patel ND, Weiss ES, Nwakanma LU, et al. Impact of donor-to-recipient weight ratio on survival after heart transplantation: analysis of the United Network for Organ Sharing Database. Circulation. 2008;118(14 suppl):S83–S88
  27. Chen JM, Sinha P, Rajasinghe HA, et al. Do donor characteristics really matter? (Short- and long-term impact of donor characteristics on recipient survival, 1995–1999). J Heart Lung Transplant. 2002;21:608–610
  28. Sethi GK, Lanauze P, Rosado LJ, et al. Clinical significance of weight difference between donor and recipient in heart transplantation. J Thorac Cardiovasc Surg. 1993;106:444–448
  29. Costanzo-Nordin MR, Liao YL, Grusk BB, et al. Oversizing of donor hearts: beneficial or detrimental?. J Heart Lung Transplant. 1991;10:717–730

PII: S1053-2498(09)00633-0

doi: 10.1016/j.healun.2009.08.007

The Journal of Heart and Lung Transplantation
Volume 29, Issue 3 , Pages 291-298 , March 2010

Article Tools

* Image Usage & Resolution