Early Experience With Lung Transplantation Using Donors After Cardiac Death

Mason, David P.; Murthy, Sudish C.; Gonzalez-Stawinski, Gonzalo V.; Budev, Marie M.; Mehta, Atul C.; McNeill, Ann M.; Pettersson, Gösta B.

doi:10.1016/j.healun.2008.01.023

« Previous Next »The Journal of Heart and Lung Transplantation
Volume 27, Issue 5 , Pages 561-563, May 2008

Early Experience With Lung Transplantation Using Donors After Cardiac Death

David P. Mason, MD
- Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
- Reprint requests: David P. Mason, MD, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, 9500 Euclid Avenue, Desk F24, Cleveland, OH 44195. Telephone: 216-444-4053. Fax: 216-445-6876.
Sudish C. Murthy, MD, PhD
- Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
Gonzalo V. Gonzalez-Stawinski, MD
- Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
Marie M. Budev, DO
- Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio.
Atul C. Mehta, MD
- Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio.
Ann M. McNeill, RN
- Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
Gösta B. Pettersson, MD, PhD
- Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio

Received 23 October 2007; received in revised form 14 January 2008; accepted 24 January 2008.

Lung transplantations that utilize donor organs after cardiac death (DCD) can substantially increase the number of available allografts for waiting recipients. Unfortunately, reported clinical outcomes are limited and widespread acceptance is slow. To further examine the potential of this modality, the results of 4 patients transplanted with DCD organs, implementing a protocol of controlled organ retrieval (Maastricht Classification III), were reviewed. There were no operative deaths; extracorporeal membrane oxygenation was required in 1 patient secondary to severe primary graft dysfunction. Three patients are alive and well at 4, 15 and 21 months; 1 patient died at 34 months with bronchiolitis obliterans syndrome, in part attributable to medication non-compliance.