The Journal of Heart and Lung Transplantation
Volume 27, Issue 4 , Pages 362-371 , April 2008

Foxp3-expressing Regulatory T Cells Expanded With CD28 Superagonist Antibody Can Prevent Rat Cardiac Allograft Rejection

  • Yusuke Kitazawa, PhD

      Affiliations

    • Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
    • Division of Immunology, Research Institute for Biological Science, Science University of Tokyo, Chiba, Japan.
    • ,
  • Masayuki Fujino, PhD

      Affiliations

    • Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
    • AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    • ,
  • Takatoshi Sakai, BS

      Affiliations

    • Shizuoka Laboratory Animal Center, Ltd., Shizuoka, Japan
    • ,
  • Haruhito Azuma, MD, PhD

      Affiliations

    • Department of Urology, Osaka Medical College, Osaka, Japan
    • ,
  • Hiromitsu Kimura, MD

      Affiliations

    • Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
    • ,
  • Yoshitaka Isaka, MD, PhD

      Affiliations

    • Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Osaka, Japan
    • ,
  • Shiro Takahara, MD, PhD

      Affiliations

    • Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Osaka, Japan
    • ,
  • Thomas Hünig, MD, PhD

      Affiliations

    • Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany
    • ,
  • Ryo Abe, MD, PhD

      Affiliations

    • Division of Immunology, Research Institute for Biological Science, Science University of Tokyo, Chiba, Japan.
    • ,
  • Xiao-Kang Li, MD, PhD

      Affiliations

    • Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
    • Corresponding Author InformationReprint requests: Xiao-Kang Li, MD, Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan. Telephone: +81-3-3416-0181. Fax: +81-3417-2816.

References 

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  13. Funeshima N, Fujino M, Kitazawa Y, et al. Inhibition of allogeneic T-cell responses by dendritic cells expressing transduced indoleamine 2,3-dioxygenase. J Gene Med. 2005;7:565–575
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 Supported by research grants from the Ministry of Education, Culture, Sports, Science and Technology of Japan (14370367, 13671250 and 17390355).

 Y.K. and M.F. contributed equally to this work.

PII: S1053-2498(08)00005-3

doi: 10.1016/j.healun.2008.01.004

The Journal of Heart and Lung Transplantation
Volume 27, Issue 4 , Pages 362-371 , April 2008

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