The Journal of Heart and Lung Transplantation
Volume 25, Issue 6 , Pages 716-725 , June 2006

Report of the Psychosocial Outcomes Workgroup of the Nursing and Social Sciences Council of the International Society for Heart and Lung Transplantation: Present Status of Research on Psychosocial Outcomes in Cardiothoracic Transplantation: Review and Recommendations for the Field

  • Sandra Cupples, DNSc, RN

      Affiliations

    • Heart Transplant Program, Washington Hospital Center, Washington, DC
    • Corresponding Author InformationReprint requests: Sandra Cupples, DNSc, Washington Hospital Center, 110 Irving Street NW, Room 1E-11, Washington, DC 20010. Telephone: 202-877-3220. Fax: 202-877-7521.
    • ,
  • Mary Amanda Dew, PhD

      Affiliations

    • Department of Psychiatry, Psychology and Epidemiology and the Artificial Heart and Adult Cardiothoracic Transplantation Programs, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, Pennsylvania
    • ,
  • Kathleen L. Grady, PhD, APN

      Affiliations

    • Bluhm Cardiovascular Institute, Division of Cardiac Surgery, Northwestern University, Chicago, Illinois
    • ,
  • Sabina De Geest, PhD, RN

      Affiliations

    • Institute of Nursing Science, University of Basel, Basel, Switzerland
    • Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    • ,
  • Fabienne Dobbels, PhD

      Affiliations

    • Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    • ,
  • Dorothy Lanuza, PhD, RN

      Affiliations

    • School of Nursing, University of Wisconsin–Madison, Madison, Wisconsin
    • ,
  • Wayne Paris, PhD

      Affiliations

    • Department of Social Work, Southern Illinois University, Carbondale, Illinois

Received 20 June 2005 ,Revised 12 December 2005 ,Accepted 11 February 2006.

References 

  1. Dew MA , Switzer GE , DiMartini AF , et al.   Psychosocial assessments and outcomes in organ transplantation . Prog Transplant . 2000;10:239–261
  2. Krakauer H , Beiley RC , Lin MJ . Beyond survival (the burden of disease in decision making in organ transplantation) . Am J Transplant . 2004;4:1555–1561
  3. De Geest S , Abraham I , Moons P , et al.   Late acute rejection and subclinical noncompliance with cyclosporine therapy in heart transplant recipients . J Heart Lung Transplant . 1998;17:854–863
  4. Dew MA , Kormos RL , Roth LH , et al.   Early posttransplant medical compliance and mental health predict physical morbidity and mortality 1 to 3 years after heart transplantation . J Heart Lung Transplant . 1999;18:549–562
  5. Dobbels F , De Geest S , Van Cleemput J , Droogne W , Vanhaecke J . Effect of late medication noncompliance on subsequent outcome after heart transplantation (a 5-year follow-up study) . J Heart Lung Transplant . 2004;23:1245–1251
  6. Cupples SA , Stilley C . Cognitive function in adult cardiothoracic candidates and recipients . J Cardiovasc Nurs . 2005;20(suppl):S74–S87
  7. Dew MA , DiMartini AF . Psychological disorders and distress after adult cardiothoracic transplantation . J Cardiovasc Nurs . 2005;20(suppl):S51–S66
  8. De Geest S , Dobbels F , Fluri C , Paris W , Troosters T . Adherence with the therapeutic regimen in heart, lung, and heart–lung transplant recipients . J Cardiovasc Nurs . 2005;20(suppl):S88–S98
  9. Grady KL , Lanuza DM . Physical functional outcomes after cardiothoracic transplantation . J Cardiovasc Nurs . 2005;20(suppl):S43–S50
  10. Paris W , White-Williams C . Social adaptation after cardiothoracic transplantation (a review of the literature) . J Cardiovasc Nurs . 2005;20(suppl):S67–S73
  11. Lanuza DM , Lefaiver C , McCabe M , Farcas GA , Garrity E . Prospective study of functional status and quality of life before and after lung transplantation . Chest . 2000;18:115–122
  12. Givertz MM , Hartley LH , Colucci WS . Long-term sequential changes in exercise capacity and chronotropic responsiveness after cardiac transplantation . Circulation . 1997;96:232–237
  13. Lands LC , Smountas AA , Mesiano G , et al.   Maximal exercise capacity and peripheral skeletal muscle function following lung transplantation . J Heart Lung Transplant . 1999;18:113–120
  14. Grady KL , Jalowiec A , White-Williams C . Improvement in quality of life in patients with heart failure who undergo transplantation . J Heart Lung Transplant . 1996;15:749–757
  15. Gross CR , Savik K , Bolman RM , Hertz MI . Long-term health status and quality of life outcomes of lung transplant recipients . Chest . 1995;108:1587–1593
  16. MacNaughton KL , Rodrigue JR , Cicale M , Staples EM . Health-related quality of life and symptom frequency before and after lung transplantation . Clin Transplant . 1998;12:320–323
  17. TenVergert EM , Essink-Bot ML , Geertsma A , et al.   The effect of lung transplantation on health-related quality of life (a longitudinal study) . Chest . 1998;113:358–364
  18. Limbos MM , Joyce DP , Chan CKN , Kesten S . Psychological functioning and quality of life in lung transplant candidates and recipients . Chest . 2000;118:408–416
  19. Lough ME , Lindsey AM , Shinn JA , Stotts NA . Impact of symptom frequency and symptom distress on self-reported quality of life in heart transplant recipients . Heart Lung . 1987;16:193–200
  20. Dumas DH , Cassidy C , Randrup E . Sexual function in men following cardiac transplantation . J Transplant Coord . 1994;4:115–118
  21. Limbos MM , Chan CK , Kesten S . Quality of life in female lung transplant candidates and recipients . Chest . 1997;112:1165–1174
  22. Lanuza DM , McCabe M , Norton-Rosko M , Corliss JW , Garrity E . Symptom experiences of lung transplant recipients (comparisons across gender, pretransplantation diagnosis, and type of transplantation) . Heart Lung . 1999;28:429–437
  23. Reyes CJ , Evangelista LS , Doering L , et al.   Physical and psychological attributes of fatigue in female heart transplant recipients . J Heart Lung Transplant . 2004;23:614–619
  24. Bunzel B , Laederach-Hofmann K . Long-term effects of heart transplantation (the gap between physical performance and emotional well-being) . Scand J Rehabil Med . 1999;31:214–222
  25. Bunzel B , Laederach-Hofmann K , Grimm M . Survival, clinical data, and quality of life 10 years after heart transplantation (a prospective study) . Zeitschrift Kardiol . 2002;91:319–327
  26. DeCampli WM , Luikart H , Hunt S , Stinson EB . Characteristics of patients surviving more than ten years after cardiac transplantation . J Thorac Cardiovasc Surg . 1995;109:1103–1115
  27. Vermeulen KM , Ouwens JP , van der Bij W , de Boer WJ , Koeter GH , TenVergert EM . Long-term quality of life in patients surviving at least 55 months after lung transplantation . Gen Hosp Psychiatry . 2003;25:95–102
  28. Hummel M , Michauk I , Hetzer R , Furhmann B . Quality of life after heart and heart–lung transplantation . Transplant Proc . 2001;33:3546–3548
  29. Dew MA , Kormos RL , DiMartini AF , et al.   Prevalence and risk of depression and anxiety-related disorders during the first three years after heart transplantation . Psychosomatics . 2001;42:300–313
  30. Grandi S , Fabbri S , Tossani E , et al.   Psychological evaluation after cardiac transplantation (the integration of different criteria) . Psychother Psychosom . 2001;70:176–183
  31. Shapiro PA , Kornfeld DS . Psychiatric outcome of heart transplantation . Gen Hosp Psychiatry . 1989;11:352–357
  32. Dobbels F , De Geest S , Martin S , et al.   Prevalence and correlates of depression symptoms at 10 years after heart transplantation (continuous attention required) . Transplant Int . 2004;17:424–431
  33. Bornstein RA , Starling RC , Myerowitz PD , Haas GJ . Neuropsychological function in patients with end-stage heart failure before and after cardiac transplantation . Acta Neurol Scand . 1995;91:260–265
  34. Riether AM , Smith SL , Lewison BJ , Cotsonis GA , Epstein CM . Quality of life changes and psychiatric and neurocognitive outcome after heart and liver transplantation . Transplantation . 1992;54:444–450
  35. Dew MA , Roth LH , Thompson ME , Kormos RL , Griffith BP . Medical compliance and its predictors in the first year after heart transplantation . J Heart Lung Transplant . 1996;15:631–645
  36. Grady KL , Jalowiec A , White-Williams C . Patient compliance at one year and two years after heart transplantation . J Heart Lung Transplant . 1998;17:383–394
  37. Paris W , Muchmore J , Pribil A , Zuhdi N , Cooper DKC . Study of relative incidences of psychosocial factors before and after heart transplantation and the influence of posttransplantation psychosocial factors on heart transplantation outcome . J Heart Lung Transplant . 1994;13:424–432
  38. Teichman BJ , Burker EJ , Weiner M , Egan TM . Factors associated with adherence to treatment regimens after lung transplantation . Prog Transplant . 2000;10:113–121
  39. Balestroni G , Bosimini E , Centofanti P , et al.   Life style and adherence to the recommended treatments after cardiac transplantation . Ital Heart J . 2002;3(suppl):652–658
  40. Nagele H , Kalmar P , Rodiger W , Stubbe HM . Smoking after heart transplantation (an underestimated hazard?) . Eur J Cardiothorac Surg . 1997;12:70–74
  41. Cherubini P , Rumiati R , Bigoni M , Tursi V , Livi U . Long-term decrease in subjective perceived efficacy of immunosuppressive treatment after heart transplantation . J Heart Lung Transplant . 2003;22:1376–1380
  42. Littlefield C , Abbey S , Fiducia D , et al.   Quality of life following transplantation of the heart, liver, and lungs . Gen Hosp Psychiatry . 1996;18(suppl):36S–47S
  43. Vermeulen KM , van der Bij W , Erasmus ME , et al.   Improved quality of life after lung transplantation in individuals with cystic fibrosis . Pediatr Pulmonol . 2004;37:419–426
  44. Bunzel B , Laederach-Hofmann K , Schubert MT . Patients benefit—partners suffer? The impact of heart transplantation on the partner relationship . Transplant Int . 1999;12:33–41
  45. Forsberg A , Lorenson U , Nilsson F , Backmana L . Pain and health related quality of life after heart, kidney and liver transplantation . Clin Transplant . 1999;13:453–460
  46. Salyer J , Flattery MP , Joyner PL , Elswick RK . Lifestyle and quality of life in long-term cardiac transplant recipients . J Heart Lung Transplant . 2003;22:309–321
  47. Hetzer R , Albert W , Hummel M , et al.   Status of patients presently living 9 to 13 years after orthotopic heart transplantation . Ann Thorac Surg . 1997;64:1661–1668
  48. Karam VH , Gasquet I , Delvart V , et al.   Quality of life in adult survivors beyond 10 years after liver, kidney and heart transplantation . Transplantation . 2003;76:1699–1704
  49. Grady KL , Jalowiec A , White-Williams C . Quality of life 6 months after heart transplantation compared with indicators of illness severity before transplantation . Am J Crit Care . 1998;7:106–116
  50. Brann WM , Bennett LE , Keck BM , Hosenpud JD . Morbidity, functional status, and immunosuppressive therapy after heart transplantation (an analysis of the Joint International Society for Heart and Lung Transplantation/United Network for Organ Sharing Thoracic Registry) . J Heart Lung Transplant . 1998;17:374–382
  51. Kavanagh T , Yacoub MH , Kennedy J , Austin PC . Return to work after transplantation (12-year follow-up) . J Heart Lung Transplant . 1999;18:846–851
  52. Paris W , Diercks M , Bright J , et al.   Returning to work after heart transplantation (a replication) . Res Soc Work Pract . 1997;7:370–377
  53. Dew MA , Switzer GE , Goycoolea JM , et al.   Does transplantation produce quality of life benefits? A quantitative analysis of the literature . Transplantation . 1997;64:1261–1273
  54. Barr ML , Schenkel FA , Van Kirk A , et al.   Determinants of quality of life changes among long-term cardiac transplant survivors (results from longitudinal data) . J Heart Lung Transplant . 2003;22:1157–1167
  55. Grady KL , Jalowiec A , White-Williams C . Preoperative psychosocial predictors of hospital length of stay after heart transplantation . J Cardiovas Nurs . 1999;14:12–26
  56. Molzahn AE , Burton JR , McCormick P , et al.   Quality of life of candidates for and recipients of heart transplants . Can J Cardiol . 1997;13:141–146
  57. Patient-reported Outcomes Measurement Information System of the National Institutes of Health. http://www.nihpromis.org. Accessed November 30, 2005.
  58. Mulligan T , Sheehan H , Hanrahan J . Sexual function after heart transplantation . J Heart Lung Transplant . 1991;10:125–128
  59. Leung TC , Ballman KV , Allison TG , et al.   Clinical predictors of exercise capacity 1 year after cardiac transplantation . J Heart Lung Transplant . 2003;22:16–27
  60. Andreassen AK , Kvernebo K , Jorgensen B , et al.   Exercise capacity in heart transplant recipients (relation to impaired endothelium-dependent vasodilation of the peripheral microcirculation) . Am Heart J . 1998;136:320–328
  61. Al-Rawas OA , Carter R , Stevenson RD , Naik SK , Wheatley DJ . Exercise intolerance following heart transplantation . Chest . 2000;118:1661–1670
  62. Vermeulen KM , Groen H , van der Bij W , et al.   The effect of bronchiolitis obliterans syndrome on health related quality of life . Clin Transplant . 2004;18:377–383
  63. Cohen L , Littlefield C , Kelly P , Maurer J , Abbey S . Predictors of quality of life and adjustment after lung transplantation . Chest . 1998;113:633–644
  64. Stilley CS , Dew MA , Stukas AA , et al.   Psychological symptom levels and their correlates in lung and heart–lung transplant recipients . Psychosomatics . 1999;40:503–509
  65. Dew MA , Simmons RG , Roth LH , et al.   Psychosocial predictors of vulnerability to distress in the year following heart transplantation . Psychol Med . 1994;24:929–945
  66. Evangelista LS , Doering L , Dracup K , Vassilakis ME , Kobashigawa JA . Hope, mood states, and quality of life in female heart transplant recipients . J Heart Lung Transplant . 2003;22:681–686
  67. Leedham B , Meyerowitz BE , Muirhead J , Frist WH . Positive expectations predict health after heart transplantation . Health Psychol . 1995;14:74–79
  68. Grimm M , Yeganehfar W , Laufer G , et al.   Cyclosporine may affect improvement of cognitive brain function after successful transplantation . Circulation . 1996;94:1339–1345
  69. Dew MA , Kormos RL , Winowich S , et al.   Quality of life outcomes after heart transplantation in individuals bridged to transplant with ventricular assist devices . J Heart Lung Transplant . 2001;20:1199–1212
  70. De Geest S , Dobbels F , Martin S , Willems K , Vanhaecke J . Clinical risk associated with appointment noncompliance in heart transplant recipients . Prog Transplant . 2000;10:162–168
  71. Shapiro PA , Williams D , Foray AT , et al.   Psychosocial evaluation and prediction of compliance problems and morbidity after heart transplantation . Transplantation . 1995;60:1462–1466
  72. Harper RG , Chacko RC , Kotik-Harper D , Young J , Gotto J . Self-reported evaluation of health behavior, stress vulnerability, and medical outcome of heart transplant recipients . Psychosom Med . 1998;60:563–569
  73. Meyendorf R , Dassing M , Scherer J , et al.   Predictive and rehabilitative perspectives in heart transplantation . Herz . 1989;14:308–321
  74. Sabati N , Snyder M , Edin-Stibbe C , Lindgren B , Finkelstein S . Facilitators and barriers to adherence with home monitoring using electronic spirometry . AACN Clin Issues . 2001;12:178–185
  75. Strauss B , Thormann T , Strenge H , et al.   Psychological, neuropsychological and neurological status in a sample of heart transplant recipients . Qual Life Res . 1992;1:119–128
  76. Salyer J , Sneed G , Corley MC . Lifestyle and health status in long-term cardiac transplant recipients . Heart Lung . 2001;30:445–457
  77. Cicutto L , Braidy C , Moloney S , et al.   Factors affecting attainment of paid employment after lung transplantation . J Heart Lung Transplant . 2004;23:481–486
  78. Caine N , Sharples LD , English TA , Wallwork J . Prospective study comparing quality of life before and after heart transplantation . Transplant Proc . 1990;22:1437–1439
  79. Paris W , Woodbury A , Thompson S , et al.   Returning to work after heart transplantation . J Heart Lung Transplant . 1993;12:46–53
  80. Grady KL , Jalowiec A , White-Williams C . Predictors of quality of life in patients at one year after heart transplantation . J Heart Lung Transplant . 1999;18:202–210
  81. Brennan AF , Davis MH , Buchholz DJ , Kuhn WF , Gray LA . Predictors of quality of life following cardiac transplantation . Psychosomatics . 1987;28:566–571
  82. Bohachick P , Taylor MV , Sereika S , Reeder S , Anton BB . Social support, personal control, and psychosocial recovery following heart transplantation . Clin Nurs Res . 2002;11:34–51
  83. Duitsman DM , Cychosz C . Psychosocial similarities and differences among employed and unemployed heart transplant recipients . J Heart Lung Transplant . 1994;13:108–115
  84. Ortalli G . Suicide by interruption of immunosuppressive therapy . J Cardiothorac Vasc Anesthesiol . 1992;6:644
  85. Ruygrok PN , Agnew TM , Coverdale HA , Whitfield C , Lambie NK . Survival after heart transplantation without regular immunosuppression . J Heart Lung Transplant . 1994;13:208–211
  86. Schweizer RT , Rovelli M , Palmeri D , et al.   Noncompliance in organ transplant recipients . Transplantation . 1990;49:374–377
  87. Rickenbacher PR , Kemna MS , Pinto FJ , et al.   Coronary artery intimal thickening in the transplanted heart (an in vivo intracoronary ultrasound study of immunologic and metabolic risk factors) . Transplantation . 1996;61:46–53
  88. Arcasoy SM , Hersh C , Christie JD , et al.   Bronchogenic carcinoma complicating lung transplantation . J Heart Lung Transplant . 2001;10:1044–1053
  89. Choi YH , Leung AN , Miro S , et al.   Primary bronchogenic carcinoma after heart or lung transplantation (radiologic and clinical findings) . J Thorac Imaging . 2000;15:36–40
  90. Curtil A , Robin J , Tronc F , et al.   Malignant neoplasms following cardiac tranplantation . Eur J Cardiothorac Surg . 1997;12:101–106
  91. Goldstein DJ , Williams DL , Oz MC , et al.   De novo solid malignancies after cardiac transplantation . Ann Thorac Surg . 1995;60:1783–1789
  92. Kobashigawa JA , Leaf DA , Lee N , et al.   A controlled trial of exercise rehabilitation after heart transplantation . N Engl J Med . 1999;340:272–277
  93. Stiebellehner L , Quittan M , End A , et al.   Aerobic endurance training program improves exercise performance in lung transplant recipients . Chest . 1998;113:906–912
  94. Dew MA , Goycoolea JM , Harris RC , et al.   An internet-based intervention to improve psychosocial outcomes in heart transplant recipients and family caregivers (development and evaluation) . J Heart Lung Transplant . 2004;23:745–758
  95. Gross CR , Kreitzer MJ , Russas V , et al.   Mindfulness meditation to reduce symptoms after organ transplant (a pilot study) . Adv Mind-Body Med . 2004;20:20–29
  96. Chlan L , Snyder M , Finkelstein S , et al.   Promoting adherence to an electronic home spirometry research program after lung transplantation . Appl Nurs Res . 1998;11:36–40
  97. Goldstein NL , Snyder M , Edin C , Lindgren B , Finkelstein SM . Comparison of two teaching strategies (adherence to a home monitoring program) . Clin Nurs Res . 1996;5:150–166
  98. Testa MA , Simonson DC . Assessment of quality-of-life outcomes . N Engl J Med . 1996;334:835–840
  99. Ware JE . Conceptualization and measurement of health-related quality of life (comments on an evolving field) . Arch Phys Med and Rehabil . 2003;84(suppl 2):S43–S51

PII: S1053-2498(06)00158-6

doi: 10.1016/j.healun.2006.02.005

The Journal of Heart and Lung Transplantation
Volume 25, Issue 6 , Pages 716-725 , June 2006

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