The Journal of Heart and Lung Transplantation
Volume 25, Issue 6 , Pages 726-729 , June 2006

Sirolimus for Kaposi’s Sarcoma

  • Cara A. Wasywich, MD

      Affiliations

    • Green Lane Cardiovascular Service, Auckland District Health Board, Auckland, New Zealand
    • Corresponding Author InformationReprint requests: Cara A. Wasywich, MD, Green Lane Cardiovascular Service, Auckland City Hospital, Level 3, Park Road Grafton, Auckland 1003, New Zealand. Telephone: 64-93-07-49-49 (ext. 23670). Fax: 64-96-31-07-33.
    • ,
  • Margaret C. Croxson, MD

      Affiliations

    • Green Lane Cardiovascular Service, Auckland District Health Board, Auckland, New Zealand
    • ,
  • Gerard J. van Doornum, MD

      Affiliations

    • Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • H. Arthur Coverdale, MD

      Affiliations

    • Green Lane Cardiovascular Service, Auckland District Health Board, Auckland, New Zealand
    • ,
  • Peter N. Ruygrok, MD

Received 19 June 2005 ,Revised 20 December 2005 ,Accepted 23 January 2006.

References 

  1. Woodle ES , Hanaway M , Buell J , et al.   Kaposi sarcoma (an analysis of the US and international experiences from the Israel Penn International Transplant Tumor Registry) . Transplant Proc . 2001;33:3660–3661
  2. Luppi M , Barozzi P , Santagostino G , et al.   Molecular evidence of organ-related transmission of Kaposi sarcoma–associated herpesvirus or human herpesvirus-8 in transplant patients . Blood . 2000;96:3279–3281
  3. Barozzi P , Luppi M , Facchetti F , et al.   Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors . Nature Med . 2003;9:554–561
  4. Emond JP , Marcelin AG , Dorent R , et al.   Kaposi’s sarcoma associated with previous human herpesvirus 8 infection in heart transplant recipients . J Clin Microbiol . 2002;40:2217–2219
  5. Briz M , Alonso-Pulpon L , Crespo-Leiro MG , et al.   Detection of herpesvirus-like sequences in Kaposi’s sarcoma from heart transplant recipients . J Heart Lung Transplant . 1998;17:288–293
  6. Fonseca R , Witzig TE , Olson LJ , et al.   Disseminated Kaposi’s sarcoma after heart transplantation (association with Kaposi’s sarcoma-associated herpesvirus) . J Heart Lung Transplant . 1998;17:732–736
  7. Demirag A , Hizel N , Karakayali H , et al.   Kaposi sarcoma–associated herpesvirus/human herpesvirus type 8 and Epstein–Barr virus in immunosuppressed renal transplant recipients . Transplant Proc . 1998;30:3166–3167
  8. Stallone G , Schena A , Infante B , et al.   Sirolimus for Kaposi’s sarcoma in renal transplant recipients . N Engl J Med . 2005;352:1317–1323
  9. Arican A , Karakayali H , Bilgin N , Haberal M . Results of treatment in renal transplant patients with Kaposi sarcoma (one-center experience) . Transplant Proc . 2000;32:626–628
  10. Kim S , Kang SH , Moon J , et al.   Kaposi sarcoma in renal transplant recipients . Transplant Proc . 1998;30:3165
  11. Keogh A , Richardson M , Ruygrok P , et al.   Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years (a randomized clinical trial) . Circulation . 2004;110:2694–2700
  12. Eisen HJ , Tuzcu EM , Dorent R , et al.   Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients . N Engl J Med . 2003;349:847–858
  13. Hussein MM , Mooij JM , Roujouleh HM . Regression of post-transplant Kaposi sarcoma after discontinuing cyclosporin and giving mycophenolate mofetil instead . Nephrol Dial Transplant . 2000;15:1103–1104

PII: S1053-2498(06)00107-0

doi: 10.1016/j.healun.2006.01.010

The Journal of Heart and Lung Transplantation
Volume 25, Issue 6 , Pages 726-729 , June 2006

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