Registry of the International Society for Heart and Lung Transplantation: Twenty-second Official Adult Heart Transplant Report—2005

Number of heart transplant procedures reported to the Registry by year.

Distribution of heart transplants stratified by average annual center volume for heart transplants performed January 1, 1997 through June 30, 2004.

Age distribution of heart transplant recipients by era for heart transplants performed January 1982 through June 30, 2003.

Anti-lymphocyte antibody use for induction immunosuppression by year of heart transplant performed January 2001 through June 2004. ATG, anti-thymocyte globulin; ALG, anti-lymphocyte globulin; IL-2R, interleukin-2 receptor.

Maintenance immunosuppression agents at 1 year post-transplantation reported for 1998, 2002 and January to June 2004. Different patients analyzed in each time period. MMF, mycophenolate mofetil.

Kaplan-Meier survival for heart transplants performed between January 1982 and June 2003. Conditional half-life = time to 50% survival for those recipients surviving the first year post-transplantation.

Kaplan-Meier survival by era for heart transplants performed between January 1982 and June 2003.

Kaplan-Meier survival for heart transplants undergoing simultaneous kidney transplantation compared with heart-alone transplantation performed between January 1982 and June 2003.

Kaplan-Meier survival for heart transplant recipients undergoing subsequent (late) kidney transplantation compared with heart-alone transplantation performed between January 1982 and June 2003. Median time to kidney transplant = 8.0 years after heart transplant.

Effect of recipient age on 1-year mortality for heart transplants performed between January 1996 and June 2003 by era of transplantation (for 1996 to 1999 analysis: N = 13,365; for 2000 to 6/2003 analysis: N = 9,743).

Effect of donor age on 1-year mortality for heart transplants performed between January 1996 and June 2003 by era of transplantation (for 1996 to 1999 analysis: N = 13,365; for 2000 to 6/2003 analysis: N = 9,743).

Percentage of adult heart transplant recipients treated for rejection during the first year post-transplantation stratified by anti-lymphocyte antibody use, age and gender.

Percentage of adult heart transplant recipients treated for rejection during the first year post-transplantation stratified by immunosuppressive medications at transplant discharge, age and gender.

Kaplan-Meier freedom from cardiac allograft vasculopathy and freedom from severe renal dysfunction for heart transplants with follow-up data between April 1994 and June 2004.

Five-year predicted survival curves for a hypothetical 30-year-old woman.

Ten-year conditional predicted survival curve for a hypothetical 30-year-old woman (conditional on survival to 3 years post-transplant).

Five-year predicted survival curves for hypothetical 63-year-old man.

Ten-year conditional predicted survival curve for hypothetical 63-year-old man (conditional on survival to 3 years post-transplant).