The Journal of Heart and Lung Transplantation
Volume 23, Issue 12 , Pages 1339-1344 , December 2004

Transplantation using hearts from primary pulmonary hypertensive donors for recipients with a high pulmonary vascular resistance

  • Emma J. Birks, MRCP

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • ,
  • Magdi H. Yacoub, DSc (FRS)

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • ,
  • Ani Anyanwu (FRCS)

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • ,
  • Rosemary Radley Smith (FRCP)

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • ,
  • Nicholas R. Banner (FRCP)

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • ,
  • Asghar Khaghani (FRCS)

      Affiliations

    • Royal Brompton and Harefield Hospital, Harefield, Middlesex, England UK
    • Corresponding Author InformationReprint requests: Asghar Khaghani, Royal Brompton and Harefield Hospital, Hill End Road, Harefield, Middlesex, UB9 6JH England UK. Telephone: 441895828799. Fax: 441895828932

Received 19 June 2003 ,Revised 8 September 2003 ,Accepted 10 September 2003.

References 

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  3. Chen JM, Levin HR, Michler RE, Prusmack CJ, Rose EA, Aaronson KD. Reevaluating the significance of pulmonary hypertension before cardiac transplantation (determination of optimal thresholds and quantification of the effect of reversibility on peri-operative mortality). J Thorac Cardiovasc Surg. 1997;114:627–634
  4. Yacoub MH, Khaghani A, Fitzgerald M, Banner NR, Radley-Smith R. Cardiac transplantation from live donors. J Am Coll Cardiol. 1988;11:102A
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  10. Wilhelm MJ, Pratschke J, Beato F, et al.  Activation of the heart by donor brain death accelerates acute rejection after transplantation. Circulation. 2000;02:2426–2433
  11. Pratschke J, Wilhelm MJ, Laskowski I, et al.  The influence of donor brain death on long-term function of renal allotransplants in rats. Transplant Proc. 2001;33:693–694
  12. Anyanwu A, Banner NR, Mitchell AG, Khaghani A, Yacoub MH. Low incidence and severity of transplant-associated coronary artery disease in heart transplants from live donors. J Heart Lung Transplant. 2003;22:281–286
  13. Yacoub MH. Haemodynamics of “domino” heart transplantation. The role of ventriculo-ventricular interaction and after load mismatch. G Ital Cardiol. 1997;27:540–543
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  15. Grossman W, Braunwald E. Pulmonary hypertension. In:  Braunwald E editors. Heart Disease. A Textbook of Cardiovascular Medicine. 3rd ed.. Philadelphia: WB Saunders; 1988;p. 793–818
  16. Fonger JD, Borkon M, Baumgartner WA, Achuff SC, Augustine S, Reitz BA. Acute right ventricular failure following heart transplantation (improvement with prostaglandin E-1 and right ventricular assist). J Heart Lung Transplant. 1986;5:317–321
  17. Kendall SW, Bittner HB, Peterseim DS, Campbell KA, Van Trigt P. Right ventricular function in the donor heart. Eur J Cardiothorac Surg. 1997;11:609–615
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  21. Yacoub MH. Two hearts that beat as one. Circulation. 1995;92:160–161
  22. Novitzky D, Rose AG, Cooper DK. Injury of myocardial conduction tissue and coronary artery smooth muscle following brain death in the baboon. Transplantation. 1988;45:964–966
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  24. Mehra MR, Prasad A, Uber PA, Park M, Scott R. The impact of explosive brain death on the genesis of cardiac allograft vasculopathy (an intravascular ultrasound study). (Abstract) J Heart Lung Transplant. 1999;18:49
  25. Ojo AO, Held PJ, Port FK, et al.  Chronic renal failure after transplantation of a nonrenal organ. New Engl J Med. 2003;340:931–940
  26. Cooper JD. Dominoes—pragmatism or piracy?. Transplant Int. 1999;4:1–2
  27. Madden B, Radley-Smith R, Hoson M, Khaghani A, Yacoub M. Medium-term results of heart and lung transplantation. J Heart Lung Transplant. 1992;11:8241–8243

PII: S1053-2498(03)00482-0

doi: 10.1016/j.healun.2003.09.026

The Journal of Heart and Lung Transplantation
Volume 23, Issue 12 , Pages 1339-1344 , December 2004

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