The Journal of Heart and Lung Transplantation
Volume 23, Issue 6 , Pages 763-766 , June 2004

Bronchial artery revascularization restores peribronchial tissue oxygenation after lung transplantation

  • Markus Kamler, MD

      Affiliations

    • Department of Thoracic and Cardiovascular Surgery, University of Essen, Essen, Germany
    • Corresponding Author InformationReprint requests: Markus Kamler, Department of Thoracic and Cardiovascular Surgery, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany. Telephone: 49-201-723-4904. Fax: 49-201-723-5451.
    • ,
  • Kai Nowak, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    • ,
  • Matthias Bock, MD

      Affiliations

    • Department of Experimental Surgery, University of Heidelberg, Heidelberg, Germany
    • ,
  • Ulf Herold, MD

      Affiliations

    • Department of Thoracic and Cardiovascular Surgery, University of Essen, Essen, Germany
    • ,
  • Johann Motsch, MD

      Affiliations

    • Department of Anaesthesiology, University of Heidelberg, Heidelberg, Germany
    • ,
  • Siegfried Hagl, MD

      Affiliations

    • Bozen Hospital, Bozen, Italy
    • ,
  • MarthaMaria Gebhard, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    • ,
  • Heinz Jakob, MD

      Affiliations

    • Department of Thoracic and Cardiovascular Surgery, University of Essen, Essen, Germany

Received 7 January 2003 ,Revised 22 May 2003 ,Accepted 21 July 2003.

References 

  1. Deffebach ME, Charan NB, Lakshminarayan S, Butler J. The bronchial circulation. Small, but a vital attribute of the lung. Am Rev Respir Dis. 1987;135:463–481
  2. Norgaard MA, Hove JD, Efsen F, Saunamaki K, Hesse B, Pettersson G. Human bronchial artery blood flow after lung Tx with direct bronchial artery revascularization. J Appl Physiol. 1999;87:1234–1239
  3. Norgaard MA, Olsen PS, Svendsen UG, Pettersson G. Revascularization of the bronchial arteries in lung transplantation (An overview). Ann Thorac Surg. 1996;62:1215–1221
  4. Ware LB, Golden JA, Finkbeiner WE, Matthay MA. Alveolar epithelial fluid transport capacity in reperfusion lung injury after lung transplantation. Am J Respir Crit Care Med. 1999;159:980–988
  5. Fehrenbach H, Wahlers T, Ochs M, et al.  Ultrastructural pathology of the alveolar type II pneumocytes of human donor lungs. Electron microscopy, stereology, and microanalysis. Virchows Arch. 1998;432:229–239
  6. Nowak K, Kamler M, Bock M, et al.  Bronchial artery revascularization affects graft recovery after lung transplantation. Am J Respir Crit Care Med. 2002;165:216–220
  7. Berti A, Nazari S, Rescigno G. The backflow from the pulmonary circulation for identification of the aortic origin of the bronchial arteries in experimental left single lung transplantation. Eur Surg Res. 1995;27:176–183
  8. Herold U, Jakob H, Kamler M, et al.  Interruption of bronchial circulation leads to a severe decrease in peribronchial oxygen tension in standard lung transplantation technique. Eur J Cardiothorac Surg. 1998;13:176–183
  9. Bergmeyer HU. Methods of enzymatic analysis. VCH Verlagsgesellschaft, Weinheim, Germany ; 1983.
  10. Aoki M, Schafers HJ, Inui K, et al.  Bronchial circulation after experimental lung transplantation (The effect of direct revascularization of a bronchial artery). Eur J Cardiothorac Surg. 1991;5:561–565
  11. Patterson GA. Airway revascularization (Is it necessary?). Ann Thorac Surg. 1993;56:807–808
  12. Patterson GA, Todd TR, Cooper JD, Pearson FG, Winton TL, Maurer J. Airway complications after double lung transplantation. Toronto Lung Transplant Group. J Thorac Cardiovasc Surg. 1990;99:14–20
  13. Schafers HJ, Haydock DA, Cooper JD. The prevalence and management of bronchial anastomotic complications in lung transplantation. J Thorac Cardiovasc Surg. 1991;101:1044–1052
  14. Sundset A, Tadjkarimi S, Khaghani A, Kvernebo K, Yacoub MH. Human en bloc double-lung transplantation (Bronchial artery revascularization improves airway perfusion). Ann Thorac Surg. 1997;63:790–795
  15. Norgaard MA, Andersen CB, Pettersson G. Airway epithelium of transplanted lungs with and without direct bronchial artery revascularization. Eur J Cardiothorac Surg. 1999;15:37–44
  16. Hyytinen TA, Heikkila LJ, Verkkala KA, et al.  Bronchial artery revascularization improves tracheal anastomotic healing after lung transplantation. Scand Cardiovasc J. 2000;34:213–218
  17. Norgaard MA, Andersen CB, Pettersson G. Does bronchial artery revascularization influence results concerning bronchiolitis obliterans syndrome and/or obliterative bronchiolitis after lung transplantation?. Eur J Cardiothorac Surg. 1998;14:311–318
  18. Baudet EM, Dromer C, Dubrez J, et al.  Intermediate-term results after en bloc double-lung transplantation with bronchial arterial revascularization. Bordeaux Lung and Heart–Lung Transplant Group. J Thorac Cardiovasc Surg. 1996;112:1292–1299

☆ Supported by the Forschungsschwerpunkt Transplantation of the University of Heidelberg.

PII: S1053-2498(03)00352-8

doi: 10.1016/j.healun.2003.07.016

The Journal of Heart and Lung Transplantation
Volume 23, Issue 6 , Pages 763-766 , June 2004

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