The Journal of Heart and Lung Transplantation
Volume 21, Issue 11 , Pages 1153-1160 , November 2002

Maximizing use of organs recovered from the cadaver donor: cardiac recommendations1 March 28–29, 2001, Crystal City, Va

  • Jonathan G Zaroff, MD

      Affiliations

    • University of California–San Francisco, San Francisco, California, USA
    • Corresponding Author InformationReprint requests: Dr. Jonathan G. Zaroff, University of California–San Francisco Medical Center, 505 Parnassus Avenue, Moffitt Suite 1176, San Francisco, California 94143-0124, USA. Telephone: 415-502-4597. Fax: 415-476-0424
    • Conference Co-Chair
  • ,
  • Bruce R Rosengard, MD

      Affiliations

    • University of Pennsylvania, Philadelphia, Pennsylvania, USA
    • Conference Co-Chair
  • ,
  • William F Armstrong, MD

      Affiliations

    • University of Michigan, Ann Arbor, Michigan, USA
  • ,
  • Wayne D Babcock, BSN

      Affiliations

    • California Transplant Donor Network, Oakland, California, USA
  • ,
  • Anthony D’Alessandro, MD

      Affiliations

    • University of Wisconsin, Madison, Wisconsin, USA
  • ,
  • G.William Dec, MD

      Affiliations

    • Massachusetts General Hospital, Harvard University, Boston Massachusetts, USA
  • ,
  • Niloo M Edwards, MD

      Affiliations

    • Columbia, University, New York, New York, USA
  • ,
  • Robert S Higgins, MD

      Affiliations

    • Virginia Commonwealth University, Richmond, Virginia, USA
  • ,
  • Valluvan Jeevanandum, MD

      Affiliations

    • University of Chicago, Chicago, Illinois, USA
  • ,
  • Myron Kauffman, MD

      Affiliations

    • United Network for Organ Sharing, Richmond, Virginia, USA
  • ,
  • James K Kirklin, MD

      Affiliations

    • University of Alabama at Birmingham, Birmingham, Alabama, USA
  • ,
  • Stephen R Large, MD

      Affiliations

    • Papworth Hospital, Cambridge, United Kingdom
  • ,
  • Daniel Marelli, MD

      Affiliations

    • University of California–Los Angeles, Los Angeles, California, USA
  • ,
  • Tammie S Peterson, RN

      Affiliations

    • Southwest Transplant Alliance, Tyler, Texas, USA
  • ,
  • W.Steves Ring, MD

      Affiliations

    • University of Texas Southwestern, Dallas, Texas, USA
  • ,
  • Robert C Robbins, MD

      Affiliations

    • Stanford University, Palo Alto, California, USA
  • ,
  • Stuart D Russell, MD

      Affiliations

    • Duke University, Durham, North Carolina, USA
  • ,
  • David O Taylor, MD

      Affiliations

    • Cleveland Clinic Foundation, Cleveland, Ohio, USA
  • ,
  • Adrian Van Bakel, MD

      Affiliations

    • Medical University of South Carolina, Charleston, South Carolina, USA
  • ,
  • John Wallwork, MB

      Affiliations

    • Papworth Hospital, Cambridge, United Kingdom
  • ,
  • James B Young, MD

      Affiliations

    • Cleveland Clinic Foundation, Cleveland, Ohio, USA

Received 7 March 2002 ,Revised 21 May 2002 ,Accepted 23 May 2002.

References 

  1. Gridelli B, Remuzzi G. Strategies for making more organs available for transplantation. N Engl J Med. 2000;343:404–410
  2. Costanzo MR, Augustine S, Bourge R, et al.  Selection and treatment of candidates for heart transplantation (a statement for health professionals from the Committee on Heart Failure and Cardiac Transplantation of the Council on Clinical Cardiology, American Heart Association). Circulation. 1995;92:3593–3612
  3. 1999 Annual Report of the U.S. Scientific Registry of Transplant Recipients and the Organ Procurement and Transplantation Network (Transplant Data 1989-1998). Richmond, Va: HHS/GRSA/OSP/DOT and United Network for Organ Sharing; 1999;
  4. Minimum Procurement Standards for an Organ Procurement Organization (OPO). Richmond. Va: United Network for Organ Sharing; 1998;
  5. Hunt SA, Baldwin J, Baumgartner W, et al.  Cardiovascular management of a potential heart donor (a statement from the Transplantation Committee of the American College of Cardiology). Crit Care Med. 1996;24:1599–1601
  6. Sweeney MS, Lammermeier DE, Frazier OH, et al.  Extension of donor criteria in cardiac transplantation (surgical risk versus supply-side economics). Ann Thorac Surg. 1990;50:7–10 discussion 10–11
  7. Jeevanandam V, Furukawa S, Prendergast TW, et al.  Standard criteria for an acceptable donor heart are restricting heart transplantation. Ann Thorac Surg. 1996;62:1268–1275
  8. Hosenpud JD, Bennett LE, Keck BM, et al.  The Registry of the Interna- tional Society for Heart and Lung Transplantation (sixteenth official report—1999). J Heart Lung Transplant. 1999;18:611–626
  9. Cardiac Transplant Research Database Group Young JB, Naftel DC, Bourge RC, et al.  Matching the heart donor and heart transplant recipient (clues for successful expansion of the donor pool: a multivariable, multiinstitutional report). J Heart Lung Transplant. 1994;13:353–364
  10. Baldwin JC, Anderson JL, Boucek MM, et al.  24th Bethesda Conferencecardiac transplantation (Task Force 2: donor guidelines). J Am Coll Cardiol. 1993;22:15–20
  11. Laks H, Marelli D. The alternate recipient list for heart transplantation (a model for expansion of the donor pool). Adv Card Surg. 1999;11:233–244
  12. Anderson JR, Hossein-Nia M, Brown P, et al.  Donor cardiac troponin-T predicts subsequent inotrope requirements following cardiac transplantation. Transplantation. 1994;58:1056–1057
  13. Vijay P, Scavo VA, Morelock RJ, et al.  Donor cardiac troponin T (a marker to predict heart transplant rejection). Ann Thorac Surg. 1998;66:1934–1939
  14. Grant JW, Canter CE, Spray TL, et al.  Elevated donor cardiac troponin 1 (a marker of acute graft failure in infant heart recipients). Circulation. 1994;90:2618–2621
  15. Potapov EV, Ivanitskaia EA, Loebe M, et al.  Value of cardiac troponin I and T for selection of heart donors and as predictors of early graft failure. Transplantation. 2001;71:1394–1400
  16. Rayburn BK, Burton TM, Wannenburg T, et al.  Are efforts at expanding the donor pool misdirected?. J Heart Lung Transplant. 1998;17:998–1003
  17. Kono T, Nishina T, Morita H, et al.  Usefulness of low-dose dobutamine stress echocardiography for evaluating reversibility of brain death induced myocardial dysfunction. Am J Cardiol. 1999;84:578–582
  18. Milano A, Livi U, Casula R, et al.  Influence of marginal donors on early results after heart transplantation. Transplant Proc. 1993;25:3158–3159
  19. Lewandowski TJ, Aaronson KD, Pietroski RE, et al.  Discordance in interpretations of potential donor echos. J Heart Lung Transplant. 1998;17:100
  20. Wheeldon DR, Potter CD, Oduro A, et al.  Transforming the “unacceptable” donor (outcomes from the adoption of a standardized donor management technique). J Heart Lung Transplant. 1995;14:734–742
  21. Van Bakel AB. identification, assessment, and management. Am J Med Sci. 1997;314:153–163
  22. Yokoyama Y, Cooper DK, Sasaki H, et al.  Donor-heart evaluation by monitoring the left ventricular pressure-volume relationship (clinical observations). J Heart Lung Transplant. 1992;11:685–692
  23. Powner DJ, Darby JM. Management of variations in blood pressure during care of organ donors. Prog Transplant. 2000;10:25–30
  24. Powner DJ, Kellum JA. Maintaining acid-base balance in organ donors. Prog Transplant. 2000;10:98–105
  25. Novitzky D, Cooper DK, Reichart B. Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation. 1987;43:852–854
  26. Novitzky D, Cooper DK, Chaffin JS, et al.  Improved cardiac allograft function following triiodothyronine therapy to both donor and recipient. Transplantation. 1990;49:311–316
  27. Jeevanandam V. Triiodothyronine (spectrum of use in heart transplantation). Thyroid. 1997;7:139–145
  28. Pennefather SH, Bullock RE, Mantle D, et al.  Use of low dose arginine vasopressin to support brain-dead organ donors. Transplantation. 1995;59:58–62
  29. Katz K, Lawler J, Wax J, et al.  Vasopressin pressor effects in critically ill children during evaluation for brain death and organ recovery. Resuscitation. 2000;47:33–40
  30. Wheeldon DR, Potter CD, Jonas M, et al.  Using “unsuitable” hearts for transplantation. Eur J Cardiothorac Surg. 1994;8:7–9 discussion 10–11
  31. Holmquist M, Chabalewski F, Blount T, et al.  A critical pathway (guiding care for organ donors). Crit Care Nurse. 1999;19:84–100
  32. Laks H, Marelli D, Fazio D, et al.  Intermediate term results of the alternate recipient list for heart transplantation. J Heart Lung Transplant. 2000;19:39

 “Maximizing Use of Organs Recovered From the Cadaver Donor” consensus conference report, March 28 and 29, 2001 Crystal City, Virginia. The conference was conducted with financial and other support from the American Society of Transplantation, the American Society of Transplant Surgeons, and the International Society for Heart and Lung Transplantation.

PII: S1053-2498(02)00526-0

The Journal of Heart and Lung Transplantation
Volume 21, Issue 11 , Pages 1153-1160 , November 2002