The Journal of Heart and Lung Transplantation
Volume 21, Issue 11 , Pages 1242-1245 , November 2002

Late Aspergillus fumigatus endomyocarditis with brain abscess as a lethal complication after heart transplantation

  • Florian Rueter, MD

      Affiliations

    • University Clinic for Cardiothoracic Surgery, Department of Surgery, University Clinics Basel, Basel, Switzerland
    • Corresponding Author InformationReprint requests: Dr Florian Rueter, University Clinic for Cardiothoracic Surgery, Department of Surgery, Kantonsspital Basel, Spitalstrasse 21, CH-4031 Basel, Switzerland. Telephone: +41-61-265-7758. Fax: +41-61-265-7537
    • F.R. and H.H.H. contributed equally to this work.
  • ,
  • Hans H Hirsch, MD, MSc

      Affiliations

    • Division Infectious Diseases, Department of Internal Medicine, University Clinics Basel, Basel, Switzerland
    • F.R. and H.H.H. contributed equally to this work.
  • ,
  • Franziska Kunz, MD

      Affiliations

    • Institute for Pathology, University Clinics Basel, Basel, Switzerland
  • ,
  • Peter Buser, MD

      Affiliations

    • Department of Cardiology, University Clinics Basel, Basel, Switzerland
  • ,
  • James M Habicht, MD

      Affiliations

    • University Clinic for Cardiothoracic Surgery, Department of Surgery, University Clinics Basel, Basel, Switzerland
  • ,
  • Holger Moch, MD

      Affiliations

    • Institute for Pathology, University Clinics Basel, Basel, Switzerland
  • ,
  • Ursula Fluckiger, MD

      Affiliations

    • Division Infectious Diseases, Department of Internal Medicine, University Clinics Basel, Basel, Switzerland
  • ,
  • Hans-Reinhard Zerkowski, MD

      Affiliations

    • University Clinic for Cardiothoracic Surgery, Department of Surgery, University Clinics Basel, Basel, Switzerland

Received 28 August 2001 ,Revised 13 December 2001 ,Accepted 7 February 2002.

References 

  1. Bourge RC, Naftel DC, Costanzo-Nordin M, et al.  Pretransplantation risk factors for death after heart transplantation. A multiinstitutional study. J Heart Lung Transplant. 1993;12:549–562
  2. Fishman JA, Rubin R. Infection in organ-transplant recipients. N Engl J Med. 1998;338:1741–1751
  3. Denning DW. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis. 1996;23:608–615
  4. Grossi P, Farina C, Fiocchi R, Dalla Gasperina D. Prevalence and outcome of invasive fungal infections in 1,963 thoracic organ transplant recipients. Transplantation. 2000;70:112–116
  5. Stevens DA, Kan VL, Judson MA, Morrison VA, Dummer S, Denning DW, et al. Practice guidelines for diseases caused by Aspergillus. Infectious Diseases Society of America. Clin Infect Dis. 2000;30:696–709
  6. Habicht JM, Passweg J, Kuhne T, Leibundgut K, Zerkowski HR. Successful local excision and long-term survival for invasive pulmonary aspergillosis during neutropenia after bone marrow transplantation. J Thorac Cardiovasc Surg. 2000;119:1286–1287
  7. Paterson DL, Dominguez EA, Chang FY, Snydman DR, Singh N. Infective endocarditis in solid organ transplant recipients. Clin Infect Dis. 1998;26:689–694
  8. Latge JP. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev. 1999;12:310–350
  9. Hirsch HH, Meylan PR, Iten A, Battegay M, Erb P. HIV-1-infected patients with focal neurologic signs: diagnostic role of PCR for Toxoplasma gondii, Epstein-Barr virus, and JC virus. Clin Microbiol Infect. 1998;4:577–584

PII: S1053-2498(02)00426-6

The Journal of Heart and Lung Transplantation
Volume 21, Issue 11 , Pages 1242-1245 , November 2002