The Journal of Heart and Lung Transplantation
Volume 21, Issue 3 , Pages 297-310 , March 2002

Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria

  • Marc Estenne, MD

      Affiliations

    • Erasme University Hospital, Brussels, Belgium
    • ,
  • Janet R Maurer, MD

      Affiliations

    • Cleveland Clinic Foundation, Cleveland, Ohio, USA
    • ,
  • Annette Boehler, MD

      Affiliations

    • University Hospital, Zurich, Switzerland
    • ,
  • James J Egan, MD

      Affiliations

    • Mater Misericordiae Hospital, Dublin, Ireland
    • ,
  • Adaani Frost, MD

      Affiliations

    • Baylor College of Medicine and Methodist Hospital, Houston, Texas USA
    • ,
  • Marshall Hertz, MD

      Affiliations

    • University of Minnesota, Minneapolis, Minnesota, USA
    • ,
  • George B Mallory Jr, MD

      Affiliations

    • Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA
    • ,
  • Gregory I Snell, MD

      Affiliations

    • Alfred Hospital, Prahan, Australia
    • ,
  • Samuel Yousem, MD

      Affiliations

    • Presbyterian University Hospital, Pittsburgh, Pennsylvania.USA

Received 1 October 2001 ,Accepted 20 December 2001.

  • Image Result

    Event 1: drop below bos threshold, not validated by second measurement. event 2: first bos measurement and time of onset of bos defined by validating event #3. fev1 decline = slope of values 2 and 3 a

    Event 1: drop below bos threshold, not validated by second measurement. event 2: first bos measurement and time of onset of bos defined by validating event #3. fev1 decline = slope of values 2 and 3 and any additional measurement over a 1–3 month period.

  • Image Result
    Though initial decline below bos threshold shows a steep decline (slope 1–2), preintervention value 2 which defines bos onset (and is validated by subsequent values) and subsequent values 3–5 define t

    Though initial decline below bos threshold shows a steep decline (slope 1–2), preintervention value 2 which defines bos onset (and is validated by subsequent values) and subsequent values 3–5 define the slope prior to intervention. benefit of therapeutic intervention will be defined by comparison with the slope 2–5.

PII: S1053-2498(02)00398-4

The Journal of Heart and Lung Transplantation
Volume 21, Issue 3 , Pages 297-310 , March 2002

Article Tools

* Image Usage & Resolution