The Journal of Heart and Lung Transplantation
Volume 21, Issue 3 , Pages 311-318 , March 2002

Rejection is reduced in thoracic organ recipients when transplanted in the first year of life

  • Jill E Ibrahim, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, St Louis, Missouri, USA
    • Corresponding Author InformationReprint requests: Jill E. Ibrahim, MD, Department of Pediatrics, Washington University School of Medicine, St Louis Children’s Hospital, One Children’s Place, 5S30, St Louis, Missouri 63110, USA. Telephone: 314-454-6095. Fax: 314-454-2561.
    • ,
  • Stuart C Sweet, MD

      Affiliations

    • Department of Pediatrics, Division of Pulmonary Medicine, St Louis, Missouri, USA
    • ,
  • Mindee Flippin, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, St Louis, Missouri, USA
    • ,
  • Catherine Dent, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, St Louis, Missouri, USA
    • ,
  • Eric Mendelhoff, MD

      Affiliations

    • Department of Surgery, Division of Cardiothoracic Surgery, St Louis, Missouri, USA
    • ,
  • Charles B Huddleston, MD

      Affiliations

    • Department of Surgery, Division of Cardiothoracic Surgery, St Louis, Missouri, USA
    • ,
  • Kathryn Trinkhaus, PhD

      Affiliations

    • Division of Biostatistics, Washington University School of Medicine, St Louis Children’s Hospital, St Louis, Missouri, USA
    • ,
  • Charles E Canter, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, St Louis, Missouri, USA

Received 30 April 2001 ,Revised 23 May 2001 ,Accepted 28 August 2001.

References 

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  2. Hosenspud JD, Bennett LE, Keck BM, et al.  The Registry of the International Society of Heart and Lung Transplantation (seventeenth official report—2000). J Heart Lung Transplant. 2000;19:909–931
  3. Bailey L, Roost H, Li Z, Jolley W. Host maturation after orthotopic cardiac transplantation during neonatal life. Heart Transplant. 1984;3:265–267
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  6. Webber SA, Naftel DC, Parker J, et al.  Late rejection greater than 1 year after pediatric heart transplantation (an ominous finding). J Heart Lung Transplant. 1999;18:69; abstract
  7. Boucek MM, Mathis CM, Boucek RJ, et al.  Prospective evaluation of echocardiography for primary rejection surveillance after infant heart transplantation (comparison with endomyocardial biopsy). J Heart Lung Transplant. 1994;13:66–73
  8. Marrari M, Dusquenoy RJ. Progress report on the ASHI/CAP proficiency survey program histocompatibility testing. I (HLA-A,B,C typing, antibody screening and lymphocytotoxic crossmatching. American Society for Histocompatibility and Immunogenetics. College American Pathologists). Hum Immunol. 1994;39:87–95
  9. Billingham M, Cary C, Hammond M, et al.  A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection (heart rejection study group). J Heart Lung Transplant. 1990;9:587–593
  10. Yousem S, Berry G, Cagle P, et al.  Revision of the 1990 working formulation for the classification of pulmonary allograft rejection (lung rejection study group). J Heart Lung Transplant. 1996;15:1–15
  11. Flippin MJ, Balzer DT, Murphy PR, Ruble SE, Mendeloff EN, Huddleston CB, et al. Rejection with heart failure after pediatric cardiac transplantation. Ann Thorac Surg. 1999;68:176–180
  12. Kubo S, Naftel D, Mills R, et al.  Risk factors for late recurrent rejection after heart transplantation (a multiinstitutional, multivariable analysis. Cardiac transplant research database group). J Heart Lung Transplant. 1995;14:409–418
  13. Kobashigawa J, Kirklin J, Naftel D, et al.  Pretransplantation risk factors for acute rejection after heart transplantation (a multiinstitutional study). J Heart Lung Transplant. 1993;12:355–366
  14. Jarcho J, Naftel DC, Shroyer TW, et al.  Influence of HLA mismatch on rejection after heart transplantation (a multiinstitutional study). J Heart Lung Transplant. 1994;13:583–596
  15. Schulman L, Weinberg A, McGregor C, Galatowicz M, Suciu-Foca N, Itescu S. Mismatches at the HLA-DR and HLA-B loci are risk factors for acute rejection after lung transplantation. Am J Respir Crit Care Med. 1998;157:1833–1837
  16. Bando K, Paradis I, Komatsu K, et al.  Analysis of time-dependent risks for infection, rejection, and death after pulmonary transplantation. J Thorac Cardiovasc Surg. 1995;109:49–57
  17. PHTS Data Collection and Analysis Center Pediatric Heart Transplant Study. Data analysis. November 11, 2000; Personal communication
  18. Ro PS, Spray TL, Bridges ND. Outcome of infants listed for lung or heart/lung transplantation. J Heart Lung Transplant. 1999;18:1232–1237
  19. Sweet SC, Spray TL, Huddleston CB, et al.  Pediatric lung transplantation at St. Louis Children’s Hospital, 1990–1995. Am J Respir Crit Care Med. 1997;155:1027–1035
  20. Mills RM, Naftel DC, Kirklin JK, et al.  Heart transplant rejection with hemodynamic compromise (a multiinstitutional study of the role of endomyocardial cellular infiltrate). J Heart Lung Transplant. 1997;16:813–821
  21. Balzer DT, Moorhead S, Saffitz JE, et al.  Utility of surveillance biopsies of infant heart transplant recipients. J Heart Lung Transplant. 1995;14:1095–1101
  22. West LJ, Pollock-Barziv S, Dipchand AI, et al.  ABO-incompatible heart transplantation in infants. N Engl J Med. 2001;11:793–800
  23. Flippin MS, Canter CE, Balzer DT. Increased morbidity and high variability of cyclosporine levels in pediatric heart transplant recipients. J Heart Lung Transplant. 2000;19:343–349
  24. Huddleston CB, Sweet SC, Mallory GB, Hamvas A, Mendeloff EN. Lung transplantation in very young infants. J Thorac Cardiovasc Surg. 1999;118:796–804
  25. Dent CL, Canter CE, Hirsch R, et al.  Transplant coronary artery disease in pediatric heart transplant recipients. J Heart Lung Transplant. 2000;19:240–248
  26. Kuhn MA, Jutzky KR, Deming DD, et al.  The medium-term findings in coronary arteries by intravascular ultrasound in infants and children after heart transplantation. J Am Coll Cardiol. 2000;36:250–254
  27. Canter CE, Moorhead S, Saffitz JE, Huddleston CB, Spray TL. Steroid withdrawal in the pediatric heart transplant recipient initially treated with triple immunosuppression. J Heart Lung Transplant. 1994;13:74–79

PII: S1053-2498(01)00395-3

The Journal of Heart and Lung Transplantation
Volume 21, Issue 3 , Pages 311-318 , March 2002

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