The Journal of Heart and Lung Transplantation
Volume 21, Issue 2 , Pages 260-270 , February 2002

An optimal experimental design for the development of preservative heart solutions

  • René Ferrera, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Dr. René Ferrera, INSERM, IFR39, Case 18, 22 avenue du Doyen Lépine, 69675 Bron Cedex, France. Telephone: 33-472-91-34-91. Fax: 33-472-34-18-76
    • INSERM IFR Cardiovasuculaire No. 39 and HCL, Bron, France
    • ,
  • Pierre Michel, PhD

      Affiliations

    • INSERM IFR Cardiovasuculaire No. 39 and HCL, Bron, France
    • ,
  • Guylaine Hadour, PhD

      Affiliations

    • INSERM IFR Cardiovasuculaire No. 39 and HCL, Bron, France
    • ,
  • Claire Rodriguez, MD

      Affiliations

    • INSERM IFR Cardiovasuculaire No. 39 and HCL, Bron, France
    • ,
  • Michel Ovize, MD, PhD

      Affiliations

    • INSERM IFR Cardiovasuculaire No. 39 and HCL, Bron, France
    • ,
  • Roger Phan Tan Luu, MD

      Affiliations

    • Experimental Research Methodology Laboratory, Centre St. Jérôme, University of Aix-Marseille, Marseille, France

Received 24 July 2000 ,Accepted 23 July 2001.

References 

  1. Jahania MS, Sanchez JA, Narayan P, Lasley RD, Mentzer RM. Heart preservation for transplantation (Principles and strategies). Ann Thorac Surg. 1999;68:1983–1987
  2. Schwalb H, Grinberg L, Yaroslavsky-Houminer E, Lazarovici G, Von Oppel U, Worthington M, et al. New solution for prolonged myocardial preservation for transplantation. J Heart Lung Transplant. 1998;17:222–229
  3. Ferrera R, Michel P, Hadour G, Chiari P, Chambers D, Rodriguez C. Original proceeding for long-term heart hypothermic preservation. 2000;19:792–800
  4. Copeland JG, Jones M, Spragg R, Stinson EB. In vitro preservation of canine hearts for 24 to 28 hours followed by successful orthotopic transplantation. Ann Surg. 1973;5:687–692
  5. Proctor E, Matthews G, Archibald J. Acute orthotopic transplantation of hearts stored for 72 hours. Thorax. 1971;26:99–101
  6. Campisi B, Chicco D, Vojnovic D, Phan-Tan-Luu R. Experimental design for a pharmaceutical formulation (Optimisation and robustness). J Pharm Biomed Anal. 1998;18:57–65
  7. Versyck KJ, Bernaerts K, Geeraerd AH, Van Impe JF. Introducing optimal experimental design in predictive modeling (A motivating example). Int J Food Microbiol. 1999;51:39–51
  8. Ferrera R, Larèse A, Berthod F, Guidollet J, Rodriguez C, Dureau G, et al. Quantitative reduction of MTT by heart biopsies in vitro is an index of viability. J Mol Cell Cardiol. 1993;25:1091–1099
  9. Sellevold OFM, Jynge P, Aarstad K. High performance liquid chromatography (A rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue). J Mol Cell Cardiol. 1986;18:517–517
  10. Ferrera R, Larèse A, Marcsek P, Guidollet J, Verdys M, Dittmar A, et al. Comparison of different techniques of hypothermic pig heart preservation. Ann Thorac Surg. 1994;57:1233–1239
  11. MacGoon DC. The ongoing quest for ideal myocardial protection. A catalogue of the recent English literature. J Thorac Cardiovasc Surg. 1985;89:639–653
  12. McGoon OC. The quest for ideal myocardial protection. J Thorac Cardiovasc Surg. 1980;79:150
  13. Michel P, Vial R, Ferrera R. A comparative study of the most widely used solution for cardiac graft preservation during hypothermia. Transplantation. In press. AQ1: Please provide additional/changes, etc. for authors academic degrees

PII: S1053-2498(01)00361-8

The Journal of Heart and Lung Transplantation
Volume 21, Issue 2 , Pages 260-270 , February 2002

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