Successful explantation of a ventricular assist device following fulminant influenza type A-associated myocarditis
Received 6 March 2001; accepted 7 June 2001.
Abstract
We report a case of fulminant myocarditis associated with refractory ventricular fibrillation following influenza A infection. Histologic examination was consistent with myocarditis and serology confirmed the viral etiology. The patient was supported with biventricular assist devices for 20 days during which her refractory ventricular fibrillation resolved spontaneously. This is the first documented case of resolution of prolonged ventricular fibrillation while on a ventricular assist device. This case suggests those patients with fulminant viral myocarditis and refractory ventricular arrhythmias may be supported successfully with ventricular assist devices until myocardial recovery takes place.
aDivision of Infectious Diseases University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
bDivision of Cardiology, Department of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
cDepartment of Cardiothoracic Division, Department of Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
dFox Chase Cancer Center, Philadelphia, Pennsylvania, USA
eMolecular Pathology Division, and Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Washington, DC, USA
Reprint requests: Dr. Paul C. McGovern, Infectious Diseases Division, University of Pennsylvania, 36th and Hamilton Walk, Johnson Pavilion, Philadelphia, Pennsylvania 19104 USA. Telephone: 215-662-2473. Fax: 215-349-5111